Amirnia Mehdi, Ranjkesh Mohammad-Reza, Azimpouran Mahzad, Karkon-Shayan Farid, Alikhah Hossein, Jafari-Asl Mohammadali, Piri Reza, Naghavi-Behzad Mohammad
Department of Dermatology, Tabriz University of Medical Sciences, Tabriz, Iran E-mail :
Asian Pac J Cancer Prev. 2016;17(1):425-9. doi: 10.7314/apjcp.2016.17.1.425.
Dermatoscopy can be applied to diagnose pigmented skin lesions. The aim of the present study was to compare dermatoscopic and histopathologic results in basal cell carcinoma (BCC) and melanocytic nevus of theface.
In an analytical-descriptive study, 61 patients suspected of BCC or melanocytic nevi of face were randomly selected. The skin lesions of patients were evaluated with dermatoscopic method from February 2012 to February 2014 and results were compared with pathological features of samples.
In this study, mean age of patients was 49.5±18.9. Some 25 (41%) were men and 36 (59%) were women. In 27 cases (44.3%) there was diagnosis of melanocytic nevus, in 28 cases (45.9%) diagnosis of BCC, and in 3 cases (4.9%) there was mixed diagnosis. The relationship between patients' gender and dermatoscopic diagnosis of the patients was statistically significant (P=0.001). For BCC the sensitivity and specificity of dermatoscopic method were 100% and 97% respectively and for melanocytic nevi 96.4% and 97%.
Dermatoscopic study not only can be helpful in improving clinical diagnosis while guiding missed malignant lesions to pathologic evaluations, but also could be useful in evaluating further suspicious or recurrent cases.
皮肤镜可用于诊断色素性皮肤病变。本研究的目的是比较面部基底细胞癌(BCC)和黑素细胞痣的皮肤镜检查结果与组织病理学结果。
在一项分析性描述性研究中,随机选择61例疑似面部BCC或黑素细胞痣的患者。2012年2月至2014年2月采用皮肤镜检查方法对患者的皮肤病变进行评估,并将结果与样本的病理特征进行比较。
本研究中,患者的平均年龄为49.5±18.9岁。其中男性25例(41%),女性36例(59%)。27例(44.3%)诊断为黑素细胞痣,28例(45.9%)诊断为BCC,3例(4.9%)为混合诊断。患者性别与皮肤镜诊断之间的关系具有统计学意义(P = 0.001)。对于BCC,皮肤镜检查方法的敏感性和特异性分别为100%和97%,对于黑素细胞痣分别为96.4%和97%。
皮肤镜检查不仅有助于改善临床诊断,将漏诊的恶性病变引导至病理评估,而且对进一步评估可疑或复发病例也有帮助。