Shabsigh R, Fishman I J, Quesada E T, Seale-Hawkins C K, Dunn J K
Scott Department of Urology, Baylor College of Medicine, Houston, Texas.
J Urol. 1989 Dec;142(6):1469-74. doi: 10.1016/s0022-5347(17)39128-0.
A total of 140 patients underwent penile vascular evaluation with intracavernous papaverine injection combined with duplex ultrasonography. Of these patients 8 were potent men who were evaluated for reasons other than erectile failure. These potent men were used as controls to obtain normal values. The remaining 132 patients had erectile impotence of various etiologies. Real-time imaging with high resolution, high frequency probes allowed for visualization of the cavernous arteries along the entire length in addition to accurate measurement of the diameter. Simultaneous selectively focused Doppler ultrasonography was used to measure the blood velocity and other vascular parameters in the cavernous and dorsal arteries. Comparison of measurements before and after papaverine injection allowed for objective interpretation of the injection results. The results were analyzed and compared to other data available on the same patients, such as history and physical examination, nocturnal penile tumescence, penile blood pressures, selective arteriography and dynamic cavernosography. In addition to the 8 potent men, there were 35 patients (27% of the impotent patients) whose vascular findings were normal. A total of 78 patients (59% of the impotent patients) had arterial insufficiency; a subgroup of 13 patients had the pelvic arterial steal syndrome. Dynamic cavernosography confirmed venous leak in all 19 patients (14% of the impotent patients) whose penile duplex ultrasonography suggested the possibility of a venous leak. Ten patients (7%) had prolonged erection after papaverine injection and they were managed without consequences. One patient had a small hematoma that resolved uneventfully. Penile duplex ultrasonography was a helpful and objective method to evaluate vasculogenic impotence.
共有140例患者接受了海绵体内注射罂粟碱联合双功超声的阴茎血管评估。其中8例为性功能正常的男性,评估原因并非勃起功能障碍。这些性功能正常的男性用作对照以获取正常值。其余132例患者患有各种病因的勃起功能障碍。使用高分辨率、高频探头进行实时成像,除了能准确测量直径外,还能观察海绵体动脉的全长。同时使用选择性聚焦多普勒超声测量海绵体动脉和背动脉的血流速度及其他血管参数。比较罂粟碱注射前后的测量结果有助于对注射结果进行客观解读。对结果进行分析,并与同一患者的其他可用数据进行比较,如病史、体格检查、夜间阴茎勃起、阴茎血压、选择性动脉造影和动态海绵体造影。除了8例性功能正常的男性外,有35例患者(占勃起功能障碍患者的27%)血管检查结果正常。共有78例患者(占勃起功能障碍患者的59%)存在动脉供血不足;其中13例患者患有盆腔动脉窃血综合征。动态海绵体造影证实了所有19例阴茎双功超声提示可能存在静脉漏的患者(占勃起功能障碍患者的14%)存在静脉漏。10例患者(占7%)在注射罂粟碱后出现阴茎持续勃起,经处理后未产生不良后果。1例患者出现小血肿,自行消退。阴茎双功超声是评估血管性勃起功能障碍的一种有用且客观的方法。