Sadic Murat, Atilgan Hasan Ikbal, Baskin Aylin, Cinar Alev, Koca Gokhan, Demirel Koray, Comak Aylin, Ozyurt Sinem, Yildirim Sule, Korkmaz Meliha
Department of Nuclear Medicine, Ministry of Health Ankara Training and Research Hospital, Ankara, Turkey.
Division of Nuclear Medicine, Ministry of Health Kahramanmaras Necip Fazil City Hospital, Kahramanmaras, Turkey.
J Clin Med Res. 2016 Mar;8(3):225-30. doi: 10.14740/jocmr2459w. Epub 2016 Jan 26.
We evaluated the stump region with scintigraphy and compared the correlation of treatment modalities and scintigraphic results.
Sixty-eight cases with extremity amputation were included in the study. Amputation applied cases underwent four-phase Tc-99m hydroxymethylene diphosphonate scintigraphy. Groups were performed according to the scanning time after amputation and amputation regions. After scintigraphic evaluation, results were recorded into five groups: osteomyelitis, soft-tissue infection, reactive changes secondary to surgery, chronic osteomyelitis, and normal. Post-surgical treatment modalities of the patients were determined and compared with scintigraphic results.
In the scintigraphic evaluation of stump regions of the 68 amputated cases, 34 patients had acute osteomyelitis, one had chronic osteomyelitis, 16 had soft-tissue infection, and eight had changes secondary to the surgery. Nine of 68 cases had normal scintigraphic features. In the scintigraphic evaluation, 43 patients took antibiotic treatment and 16 had surgery. There was a strong correlation between scintigraphic results and treatment approach (P < 0.0001, r = 0.803) by means of preferred therapy and effectiveness of the therapy according to the scintigraphic results. Scintigraphy need increases with age after amputation and a negative correlation between patient age and scintigraphic need was found (P < 0.02, r = -0.339). There was no pathology in the follow-up in the cases that were scintigraphically normal.
Bone scintigraphy is a cost-effective, non-invasive, and efficient method that directs treatment in the evaluation of the stump region after amputation.
我们用闪烁扫描法评估了残端区域,并比较了治疗方式与闪烁扫描结果之间的相关性。
本研究纳入了68例肢体截肢患者。截肢患者接受了四期锝-99m亚甲基二膦酸盐闪烁扫描。根据截肢后的扫描时间和截肢部位进行分组。闪烁扫描评估后,结果被记录为五组:骨髓炎、软组织感染、手术继发的反应性改变、慢性骨髓炎和正常。确定患者的术后治疗方式,并与闪烁扫描结果进行比较。
在对68例截肢患者残端区域的闪烁扫描评估中,34例患者患有急性骨髓炎,1例患有慢性骨髓炎,16例患有软组织感染,8例有手术继发改变。68例中有9例闪烁扫描特征正常。在闪烁扫描评估中,43例患者接受了抗生素治疗,16例接受了手术。根据闪烁扫描结果,通过首选治疗方法和治疗效果,闪烁扫描结果与治疗方法之间存在很强的相关性(P < 0.0001,r = 0.803)。截肢后闪烁扫描需求随年龄增加,且发现患者年龄与闪烁扫描需求之间呈负相关(P < 0.02,r = -0.339)。闪烁扫描正常的病例在随访中无病理改变。
骨闪烁扫描是一种经济有效、非侵入性且高效的方法,可在截肢后残端区域评估中指导治疗。