波兰和德国的童年逆境与成人头痛
Childhood Adversities and Adult Headache in Poland and Germany.
作者信息
Reuchlein Bettina, Henn Lea, Brian Tamara, Schier Katarzyna, Hardt Jochen
机构信息
Medizinische Psychologie und Medizinische Soziologie, Klinik für Psychosomatische Medizin und Psychotherapie, Universitätsmedizin der Johannes Gutenberg-Universität Mainz, Mainz Germany.
Faculty of Psychology, University of Warsaw, Warsaw, Poland.
出版信息
PLoS One. 2016 Feb 9;11(2):e0148162. doi: 10.1371/journal.pone.0148162. eCollection 2016.
OBJECTIVE
Various childhood adversities have been found to be associated with chronic pain in adulthood. However, associations were moderate in most studies, i.e. odds ratios (OR) were between one and two.
METHOD
An internet survey was performed in 508 Polish and 500 German subjects. A total of 19 childhood adversities were selected and their associations with headaches explored. Age, gender and country were included as potential confounders, as well as their two-way interaction with the risk factors.
RESULTS
Two strong risk factors were identified. (1) A combined score for physical and emotional neglect showed an odds ratio (OR) of 2.78 (p < .002) to the frequency of headache in adulthood as a main effect. (2) Father having had chronic pain showed an OR of 4.36 (p < .001) with headache in adulthood for women, but not for men (OR = 0.86, p < .556). The majority of the examined childhood adversities were not associated with adult headache, neither when tested individually nor as a sum score.
CONCLUSION
This study confirms results from previous ones that childhood adversities may play a role in the development of adult headache, but it is a rather minor one. Contrary to other studies, neglect turned out to be one of the strongest predictors.
目的
已发现多种童年逆境与成年后的慢性疼痛有关。然而，在大多数研究中，这种关联程度中等，即优势比（OR）在1到2之间。
方法
对508名波兰人和500名德国人进行了一项网络调查。共选取了19种童年逆境，并探究了它们与头痛的关联。将年龄、性别和国家作为潜在混杂因素，以及它们与风险因素的双向交互作用纳入研究。
结果
确定了两个强风险因素。（1）身体和情感忽视的综合得分作为主要效应，与成年后头痛频率的优势比（OR）为2.78（p <.002）。（2）父亲患有慢性疼痛，成年女性头痛的OR为4.36（p <.001），成年男性则无关联（OR = 0.86，p <.556）。所研究的大多数童年逆境与成年头痛均无关联，无论是单独测试还是作为总分测试。
结论
本研究证实了先前研究的结果，即童年逆境可能在成年头痛的发生中起作用，但作用较小。与其他研究相反，忽视被证明是最强的预测因素之一。
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