Jurair Humaira, Bhimani Amyna
Humaira Jurair, FCPS, Senior Instructor, Department of Pediatrics & Child Health, Aga Khan University Hospital, Karachi, Pakistan.
Amyna Bhimani, Diploma in Nursing, Registered Nurse, Department of Nursing Service, Aga Khan University Hospital, Karachi, Pakistan.
Pak J Med Sci. 2015 Nov-Dec;31(6):1554-7. doi: 10.12669/pjms.316.8607.
Procedural sedation and analgesia (PSA) is pharmacologically induced state which allows patients to tolerate painful procedures while maintaining protective reflexes. It is the standard of care but there is limited data from Pakistan. Our objective was to assess the safety of the procedural sedation and analgesia in pediatric population at a tertiary care setting.
A retrospective notes and record review was conducted at the Aga Khan University Hospital, Karachi over 4 years from April 2010 to August 2014. Patients were between ages 6 months to 16 years and were in low risk category. The combination of Ketamine and Propofol were used. Data collected on the standardized hospital PSA form. All procedures were performed by two trained persons.
A total of 3489 diagnostic and therapeutic procedures were performed. Satisfactory level of sedation was achieved for 3486 (99%) of procedures. Adverse events occurred in 21 (0.6%) patients including: 12 (0.3%) episodes of hypoxia, 07 (0.2%) episodes of apnea, 02 (0.06%) episodes of post sedation hallucination. No major events were noted.
Procedural sedation & analgesia for children using Propofol and Ketamine is found safe and effective in our setting.
程序性镇静镇痛(PSA)是一种药物诱导状态,可使患者在保持保护性反射的同时耐受疼痛性操作。这是护理标准,但来自巴基斯坦的数据有限。我们的目的是评估在三级医疗机构中对儿科患者进行程序性镇静镇痛的安全性。
2010年4月至2014年8月期间,在卡拉奇的阿迦汗大学医院进行了一项回顾性病历和记录审查。患者年龄在6个月至16岁之间,属于低风险类别。使用了氯胺酮和丙泊酚的联合用药。数据通过标准化的医院PSA表格收集。所有操作均由两名经过培训的人员进行。
共进行了3489例诊断和治疗操作。3486例(99%)操作达到了满意的镇静水平。21例(0.6%)患者发生了不良事件,包括:12例(0.3%)缺氧发作、7例(0.2%)呼吸暂停发作、2例(0.06%)镇静后幻觉发作。未观察到重大事件。
在我们的环境中,使用丙泊酚和氯胺酮对儿童进行程序性镇静镇痛是安全有效的。