• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

相似文献

1
Intratympanic corticosteroid for sudden hearing loss: does it really work?鼓室内注射皮质类固醇治疗突发性听力损失:真的有效吗?
Braz J Otorhinolaryngol. 2016 May-Jun;82(3):353-64. doi: 10.1016/j.bjorl.2015.06.007. Epub 2015 Nov 6.
2
Intratympanic corticosteroids for sudden sensorineural hearing loss.鼓室内皮质类固醇治疗突发性聋。
Cochrane Database Syst Rev. 2022 Jul 22;7(7):CD008080. doi: 10.1002/14651858.CD008080.pub2.
3
Short-course oral steroids as an adjunct therapy for chronic rhinosinusitis.短期口服类固醇作为慢性鼻-鼻窦炎的辅助治疗
Cochrane Database Syst Rev. 2016 Apr 26;4(4):CD011992. doi: 10.1002/14651858.CD011992.pub2.
4
Intratympanic corticosteroid injection as a first-line treatment of the patients with idiopathic sudden sensorineural hearing loss compared to systemic steroid: A systematic review and meta-analysis.鼓室内皮质类固醇注射与全身皮质类固醇治疗特发性突发性聋患者的一线治疗比较:系统评价和荟萃分析。
Am J Otolaryngol. 2022 Sep-Oct;43(5):103505. doi: 10.1016/j.amjoto.2022.103505. Epub 2022 Jun 2.
5
Intramuscular versus oral corticosteroids to reduce relapses following discharge from the emergency department for acute asthma.肌肉注射与口服皮质类固醇用于减少急性哮喘患者从急诊科出院后的复发情况。
Cochrane Database Syst Rev. 2018 Jun 2;6(6):CD012629. doi: 10.1002/14651858.CD012629.pub2.
6
Treatments for chronic inflammatory demyelinating polyradiculoneuropathy (CIDP): an overview of systematic reviews.慢性炎症性脱髓鞘性多发性神经根神经病(CIDP)的治疗:系统评价概述
Cochrane Database Syst Rev. 2017 Jan 13;1(1):CD010369. doi: 10.1002/14651858.CD010369.pub2.
7
Intratympanic steroids for sudden sensorineural hearing loss: a systematic review.鼓室内类固醇治疗突发性聋:系统评价。
Otolaryngol Head Neck Surg. 2011 Oct;145(4):534-43. doi: 10.1177/0194599811419466. Epub 2011 Aug 26.
8
Intratympanic dexamethasone in sudden sensorineural hearing loss: A systematic review and meta-analysis.鼓室内注射地塞米松治疗突发性感音神经性听力损失:一项系统评价和荟萃分析。
Laryngoscope. 2017 Aug;127(8):1897-1908. doi: 10.1002/lary.26394. Epub 2016 Nov 15.
9
Early use of inhaled corticosteroids in the emergency department treatment of acute asthma.在急诊科急性哮喘治疗中早期使用吸入性糖皮质激素。
Cochrane Database Syst Rev. 2012 Dec 12;12(12):CD002308. doi: 10.1002/14651858.CD002308.pub2.
10
Systemic and topical antibiotics for chronic rhinosinusitis.用于慢性鼻-鼻窦炎的全身及局部用抗生素
Cochrane Database Syst Rev. 2016 Apr 26;4(4):CD011994. doi: 10.1002/14651858.CD011994.pub2.

引用本文的文献

1
Intratympanic steroid as salvage therapy for sudden sensorineural hearing loss: an overview of systematic reviews and meta-analyses.鼓室内注射类固醇作为突发性感音神经性听力损失的挽救治疗:系统评价和荟萃分析概述
Eur Arch Otorhinolaryngol. 2025 Feb 17. doi: 10.1007/s00405-025-09252-9.
2
[Hormonal influence on hearing].[激素对听力的影响]
HNO. 2021 Dec;69(12):987-995. doi: 10.1007/s00106-021-01019-y. Epub 2021 Mar 16.
3
Idiopathic sudden sensorineural hearing loss: Effectiveness of salvage treatment with low-dose intratympanic dexamethasone.特发性突发性感音神经性听力损失:低剂量鼓室内注射地塞米松挽救治疗的有效性
J Otol. 2021 Jan;16(1):6-11. doi: 10.1016/j.joto.2020.06.002. Epub 2020 Jul 2.

本文引用的文献

1
Intratympanic corticotherapy and tinnitus control after sudden hearing loss.突发性听力损失后的鼓室内皮质类固醇治疗与耳鸣控制
Int Tinnitus J. 2012;17(2):186-93. doi: 10.5935/0946-5448.20120033.
2
Therapeutic efficacy of the combination of intratympanic methylprednisolone and oral steroid for idiopathic sudden deafness.鼓室内甲泼尼龙联合口服类固醇治疗特发性突发性聋的疗效。
Otolaryngol Head Neck Surg. 2013 Nov;149(5):753-8. doi: 10.1177/0194599813500754. Epub 2013 Aug 19.
3
Comparison of intermittent intratympanic steroid injection and near-continual transtympanic steroid perfusion as salvage treatments for sudden sensorineural hearing loss.间歇性鼓室内类固醇注射与持续经鼓室类固醇灌注治疗突发性聋的疗效比较。
Laryngoscope. 2013 Sep;123(9):2264-9. doi: 10.1002/lary.23909. Epub 2013 Jun 26.
4
Intratympanic and systemic steroids for sudden hearing loss.鼓室内和全身用类固醇治疗突发性聋。
Otol Neurotol. 2013 Jun;34(4):771-6. doi: 10.1097/MAO.0b013e31828bb567.
5
Systemic steroid versus combined systemic and intratympanic steroid treatment for sudden sensorineural hearing loss.全身用类固醇与全身及鼓室内联合用类固醇治疗突发性感音神经性听力损失的比较
J Craniofac Surg. 2013 Mar;24(2):432-4. doi: 10.1097/SCS.0b013e31828014e7.
6
Intratympanic steroid therapy in moderate sudden hearing loss: a randomized, triple-blind, placebo-controlled trial.鼓室内类固醇治疗中度突发性聋:一项随机、三盲、安慰剂对照试验。
Laryngoscope. 2013 Mar;123(3):774-8. doi: 10.1002/lary.23678. Epub 2013 Feb 1.
7
Efficacy of intratympanic steroid therapy for idiopathic sudden sensorineural hearing loss: comparison with systemic steroid therapy and combined therapy.鼓室内注射类固醇疗法治疗特发性突发性感音神经性听力损失的疗效:与全身类固醇疗法及联合疗法的比较
Acta Otolaryngol. 2013 May;133(5):428-33. doi: 10.3109/00016489.2012.749520. Epub 2013 Jan 28.
8
Treatment outcome of additional dextran to corticosteroid therapy on sudden deafness: propensity score-matched cohort analysis.附加右旋糖酐治疗糖皮质激素治疗突发性聋的疗效:倾向评分匹配队列分析。
Otolaryngol Head Neck Surg. 2012 Dec;147(6):1125-30. doi: 10.1177/0194599812458219. Epub 2012 Aug 21.
9
Noninvasive intratympanic dexamethasone treatment for sudden sensorineural hearing loss.非侵入性鼓室内地塞米松治疗突发性感音神经性听力损失
Acta Otolaryngol. 2012 Jun;132(6):583-9. doi: 10.3109/00016489.2011.649145. Epub 2012 Feb 19.
10
Intratympanic dexamethasone is an effective method as a salvage treatment in refractory sudden hearing loss.鼓室内地塞米松是治疗难治性突发性聋的有效方法。
Otol Neurotol. 2011 Dec;32(9):1432-6. doi: 10.1097/MAO.0b013e318238fc43.

鼓室内注射皮质类固醇治疗突发性听力损失:真的有效吗?

Intratympanic corticosteroid for sudden hearing loss: does it really work?

作者信息

Barreto Monique Antunes de Souza Chelminski, Ledesma Aleluia Lima Losno, de Oliveira Carlos Augusto Costa Pires, Bahmad Fayez

机构信息

Postgraduate Speech and Hearing, Universidade Federal de Santa Maria (UFSM), Santa Maria, RS, Brazil; Educational Psychology, Universidade Federal do Rio de Janeiro (UFRJ), Rio de Janeiro, RJ, Brazil; Audiology and Neurotology, Universidade Federal de Pernambuco (UFPE), Recife, PE, Brazil; Universidade de Brasília (UnB), Brasília, DF, Brazil.

Universidade de Brasília (UnB), Brasília, DF, Brazil.

出版信息

Braz J Otorhinolaryngol. 2016 May-Jun;82(3):353-64. doi: 10.1016/j.bjorl.2015.06.007. Epub 2015 Nov 6.

DOI:10.1016/j.bjorl.2015.06.007
PMID:26873148
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9444616/
Abstract

INTRODUCTION

Sudden deafness is characterized by an abrupt hearing loss of at least 30dB in three sequential frequencies in the standard pure tone audiogram over three days or less. Treatment is based on its etiology, and oral corticosteroids are widely used. Intratympanic corticosteroids are included as primary or secondary treatment when there is no improvement with the use of oral corticosteroids.

OBJECTIVE

To determine the effectiveness of therapy with intratympanic steroids in sudden deafness.

METHODS

A systematic review was performed of publications on the topic in the databases of PubMed/MEDLINE, with the keywords: sudden deafness, sudden hearing loss, and corticosteroids.

RESULTS

Thirty scientific studies were analyzed. As to the objectives of the study analyzed, 76.7% sought to evaluate the use of intratympanic therapy salvage after failure to conventional treatment, and intratympanic therapy was used as the primary treatment 23.3% of the studies.

CONCLUSION

Intratympanic corticosteroid therapy is prescribed primarily when there is failure of conventional therapy and when it is limited to use systemic corticosteroids, such as the diabetic patient.

摘要

引言

突发性聋的特征是在标准纯音听力图中,连续三天或更短时间内,三个连续频率的听力突然下降至少30dB。治疗基于其病因,口服糖皮质激素被广泛使用。当使用口服糖皮质激素没有改善时,鼓室内注射糖皮质激素作为主要或次要治疗方法。

目的

确定鼓室内注射糖皮质激素治疗突发性聋的有效性。

方法

在PubMed/MEDLINE数据库中对关于该主题的出版物进行系统综述,关键词为:突发性聋、突发性听力损失和糖皮质激素。

结果

分析了30项科学研究。关于所分析研究的目的,76.7%试图评估在传统治疗失败后鼓室内治疗的挽救作用,23.3%的研究将鼓室内治疗用作主要治疗方法。

结论

鼓室内糖皮质激素治疗主要在传统治疗失败以及仅限于使用全身性糖皮质激素(如糖尿病患者)时使用。