Keller Roberta L
Neonatology, Department of Pediatrics, UCSF Benioff Children's Hospital, University of California San Francisco, Box 0734, 550 16th Street, 5th Floor, San Francisco, CA 94143, USA.
Clin Perinatol. 2016 Mar;43(1):187-202. doi: 10.1016/j.clp.2015.11.013.
Pulmonary hypertension in the perinatal period can present acutely (persistent pulmonary hypertension of the newborn) or chronically. Clinical and echocardiographic diagnosis of acute pulmonary hypertension is well accepted but there are no broadly validated criteria for echocardiographic diagnosis of pulmonary hypertension later in the clinical course, although there are significant populations of infants with lung disease at risk for this diagnosis. Contributing cardiovascular comorbidities are common in infants with pulmonary hypertension and lung disease. It is not clear who should be treated without confirmation of pulmonary vascular disease by cardiac catheterization, with concurrent evaluation of any contributing cardiovascular comorbidities.
围生期肺动脉高压可急性出现（新生儿持续性肺动脉高压）或慢性出现。急性肺动脉高压的临床和超声心动图诊断已被广泛接受，但在临床病程后期，对于肺动脉高压的超声心动图诊断尚无广泛验证的标准，尽管有大量患有肺部疾病的婴儿有此诊断风险。肺动脉高压和肺部疾病婴儿常见心血管合并症。目前尚不清楚在未经心导管检查确认肺血管疾病且未同时评估任何相关心血管合并症的情况下，哪些患者应接受治疗。
