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猪异种移植治疗小儿浅Ⅱ度烧伤

Porcine xenograft treatment of superficial partial-thickness burns in paediatric patients.

作者信息

Burkey B, Davis W, Glat P M

机构信息

Stuart J. Hulnick, MD Burn Center, St. Christopher's Hospital for Children, 160 East Erie Avenue, Philadelphia, PA.

Drexel University College of Medicine.

出版信息

J Wound Care. 2016 Feb;25(2):S10-5. doi: 10.12968/jowc.2016.25.Sup2.S10.

Abstract

OBJECTIVE

Porcine xenograft (PX) has become a valuable part of the armamentarium of treatment options in a US paediatric burn centre. The use in adult patients has been well described in the burn literature, but there is minimal literature describing its use in children. The objective of this article is to describe a three-years' experience with PX use in paediatric burns.

METHOD

A retrospective medical record review of patients with superficial partial-thickness burns treated with PX admitted to a paediatric burn centre between February 2009 and November 2012.

RESULTS

A total of 164 patients met the inclusion criteria. Burn total body surface area (TBSA) ranged from 0.5% to 28%. After the placement of PX, significant decreases were seen in the need for narcotic analgesics and burn dressing changes. Only four of 164 patients (2.4%) developed infections, although only one of these infections was at the site of the xenograft.

CONCLUSION

PX appears to reduce pain and eliminate the need for procedural intravenous sedation in many patients. This can make burn wound care more child-friendly and shorten hospital length of stay. The complication rate is low and manageable. The authors believe that PX is an effective and safe treatment for superficial partial-thickness burns in children.

DECLARATION OF INTEREST

P. M.Glat, is a paid consultant and speaker for Mölnlycke Health Care, the manufacturer of EZ Derm.

摘要

目的

猪异种移植物(PX)已成为美国一家儿科烧伤中心治疗手段的重要组成部分。烧伤文献中对其在成年患者中的应用已有详尽描述,但关于其在儿童患者中的应用描述极少。本文旨在阐述三年来 PX 在儿科烧伤治疗中的应用经验。

方法

对 2009 年 2 月至 2012 年 11 月间入住一家儿科烧伤中心、接受 PX 治疗的浅Ⅱ度烧伤患者的病历进行回顾性研究。

结果

共有 164 例患者符合纳入标准。烧伤总面积(TBSA)为 0.5%至 28%。应用 PX 后,麻醉性镇痛药的使用需求及烧伤换药次数显著减少。164 例患者中仅有 4 例(2.4%)发生感染,不过其中仅 1 例感染发生在异种移植物部位。

结论

PX 似乎能减轻疼痛,并使许多患者无需进行程序性静脉镇静。这可使烧伤创面护理对儿童更友好,并缩短住院时间。并发症发生率低且可控。作者认为 PX 是治疗儿童浅Ⅱ度烧伤的一种有效且安全的方法。

利益声明

P.M. 格拉特是莫林医疗保健公司(EZ Derm 的制造商)的付费顾问及演讲者。

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