Van Camp L S C, Oldenburg J F E, Sabbe B G C
a Collaborative Antwerp Psychiatric Research Institute (CAPRI), Faculty of Medicine , University of Antwerp , Antwerp , Belgium.
b University Department, Psychiatric Hospital , Duffel , Belgium.
Cogn Neuropsychiatry. 2016;21(2):130-45. doi: 10.1080/13546805.2015.1137214. Epub 2016 Feb 15.
The pattern of associations between clinical insight, cognitive insight, and neurocognitive functioning was assessed in bipolar disorder patients.
Data from 42 bipolar disorder patients were examined. Cognitive insight was measured using the Beck Cognitive Insight Scale (BCIS). The BCIS is a 15-item self-report instrument consisting of two subscales, self-reflectiveness and self-certainty. Clinical insight was measured by the use of the item G12 of the Positive and Negative Syndrome Scale. Neurocognitive functioning was assessed using the International Society for Bipolar Disorders-Battery for Assessment of Neurocognition.
Correlation analyses revealed significant positive associations between self-reflectiveness and speed of processing, attention, working memory, visual learning, and reasoning and problem solving. The subscale self-certainty was negatively correlated to working memory, however, this correlation disappeared when we controlled for confounding variables. No correlations between clinical insight and neurocognition were found. In addition, there was no association between cognitive insight and clinical insight.
Better neurocognitive functioning was more related to higher levels of self-reflectiveness than to diminished self-certainty.
对双相情感障碍患者的临床洞察力、认知洞察力和神经认知功能之间的关联模式进行了评估。
对42名双相情感障碍患者的数据进行了检查。使用贝克认知洞察量表（BCIS）测量认知洞察力。BCIS是一种由15个项目组成的自我报告工具，包括两个子量表，即自我反思性和自我确定性。使用阳性和阴性症状量表的项目G12测量临床洞察力。使用国际双相情感障碍协会神经认知评估电池评估神经认知功能。
相关分析显示，自我反思性与加工速度、注意力、工作记忆、视觉学习以及推理和问题解决能力之间存在显著正相关。自我确定性子量表与工作记忆呈负相关，然而，当我们控制混杂变量时，这种相关性消失了。未发现临床洞察力与神经认知之间存在相关性。此外，认知洞察力与临床洞察力之间也没有关联。
更好的神经认知功能与更高水平的自我反思性更为相关，而非与降低的自我确定性相关。
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