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清醒开胸手术与化学性胸膜固定术治疗难治性继发性自发性气胸的比较

Awake thoracic surgery versus chemical pleurodesis for intractable secondary spontaneous pneumothorax.

作者信息

Noda Masafumi, Watanabe Tatsuaki, Matsuda Yasushi, Sakurada Akira, Hoshikawa Yasushi, Okada Yoshinori

机构信息

Department of Thoracic Surgery, Institute of Development, Aging and Cancer, Tohoku University, 4-1 Seiryo-machi, Aobaku, Sendai, Miyagi, 980-8575, Japan.

出版信息

Surg Today. 2016 Nov;46(11):1268-74. doi: 10.1007/s00595-016-1309-5. Epub 2016 Feb 16.

Abstract

PURPOSE

To compare the outcomes and efficacy of awake video-assisted thoracic surgery (VATS) with those of chemical pleurodesis for intractable secondary spontaneous pneumothorax (SSP).

METHODS

We analyzed, retrospectively, 60 consecutive patients who underwent awake VATS (n = 22) or chemical pleurodesis (n = 38) for SSP. Using propensity score matching, we identified comparable patient groups (n = 12 each): the awake VATS group and the chemical pleurodesis group. We compared hematologic data on postoperative day 1, postoperative complications including respiratory complications, and the maximum score on the verbal rating scale (VRS) between the groups. Next, we identified comparable patient groups (n = 8 each) for those with controlled air leak after treatment, but not for those with a prolonged air leak. We analyzed data about the day of air leak control, intra-thoracic drainage, and hospital stay to compare awake VATS vs. chemical pleurodesis.

RESULTS

After propensity score matching, the rates of recurrent pneumothorax and prolonged air leaks after conservative or surgical treatment were not significantly different. The C-reactive protein level and the VRS score were significantly lower in the awake VATS group. The duration of prolonged air leak, and drainage after treatment were significantly shorter in the awake VATS group. The postoperative hospital stay and the incidence of postoperative complications did not differ between the groups.

CONCLUSIONS

We advocate that awake VATS, performed by a skilled thoracic surgeon, is a more feasible surgical option than chemical pleurodesis for patients with intractable SSP.

摘要

目的

比较清醒电视辅助胸腔镜手术(VATS)与化学性胸膜固定术治疗难治性继发性自发性气胸(SSP)的疗效和效果。

方法

我们回顾性分析了60例连续接受清醒VATS(n = 22)或化学性胸膜固定术(n = 38)治疗SSP的患者。通过倾向评分匹配,我们确定了可比的患者组(每组n = 12):清醒VATS组和化学性胸膜固定术组。我们比较了两组术后第1天的血液学数据、包括呼吸并发症在内的术后并发症以及视觉模拟评分量表(VRS)的最高分。接下来,我们为治疗后漏气得到控制的患者确定了可比的患者组(每组n = 8),但未对漏气时间延长的患者进行此操作。我们分析了关于漏气控制日期、胸腔引流和住院时间的数据,以比较清醒VATS与化学性胸膜固定术。

结果

倾向评分匹配后,保守或手术治疗后复发性气胸和漏气时间延长的发生率无显著差异。清醒VATS组的C反应蛋白水平和VRS评分显著更低。清醒VATS组漏气时间延长的持续时间和治疗后的引流时间显著更短。两组术后住院时间和术后并发症发生率无差异。

结论

我们主张,对于难治性SSP患者,由熟练的胸外科医生进行清醒VATS是比化学性胸膜固定术更可行的手术选择。

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