Oh Jae-Sang, Yoon Seok-Mann, Oh Hyuk-Jin, Shim Jai-Joon, Bae Hack-Gun, Lee Kyeong-Seok
Department of Neurosurgery, Soonchunhyang University Cheonan Hospital, Cheonan, Korea.
J Korean Neurosurg Soc. 2016 Jan;59(1):17-25. doi: 10.3340/jkns.2016.59.1.17. Epub 2016 Jan 20.
Treatment of intracranial dural arteriovenous fistulas (dAVFs) remains a challenge. However, after introduction of Onyx, transarterial approach is the preferred treatment option in many centers. We report our experience of dAVFs embolization with special emphasis on transarterial approach.
Seventeen embolization procedures were performed in 13 patients with dAVFs between Jan 2009 and Oct 2014. Clinical symptoms, location and type of fistulas, embolization methods, complications, radiological and clinical outcomes were evaluated using charts and PACS images.
All 13 patients had symptomatic lesions. The locations of fistulas were transverse-sigmoid sinus in 6, middle fossa dura in 4, cavernous sinus in 2, and superior sagittal sinus in 1 patient. Cognard types were as follows : I in 4, IIa in 2, IIa+IIb in 5, and IV in 2. Embolization procedures were performed ≥2 times in 3 patients. Nine patients were treated with transarterial Onyx embolization alone. One of these required direct surgical puncture of middle meningeal artery. Complete obliteration of fistulas was achieved in 11/13 (85%) patients. There were no complications except for 1 case of Onyx migration in cavernous dAVF. Modified Rankin scale score at post-operative 3 months were 0 in 11, and 3 in 2 patients.
Transarterial Onyx embolization can be a first line therapeutic option in patients with dAVFs. However, transvenous approach should be tried first in cavernous sinus dAVF because of the risk of intracranial migration of liquid embolic materials. Furthermore, combined surgical endovascular approach can be considered as a useful option in inaccessible route.
颅内硬脑膜动静脉瘘(dAVF)的治疗仍然是一项挑战。然而,在引入Onyx之后,经动脉途径在许多中心成为首选的治疗选择。我们报告我们使用Onyx栓塞dAVF的经验,特别强调经动脉途径。
2009年1月至2014年10月期间,对13例dAVF患者进行了17次栓塞手术。使用图表和PACS图像评估临床症状、瘘的位置和类型、栓塞方法、并发症、影像学和临床结果。
所有13例患者均有症状性病变。瘘的位置分别为横窦乙状窦6例,中颅窝硬脑膜4例,海绵窦2例,上矢状窦1例。Cognard分型如下:I型4例,IIa型2例,IIa+IIb型5例,IV型2例。3例患者栓塞手术进行了≥2次。9例患者仅接受经动脉Onyx栓塞治疗。其中1例需要直接手术穿刺脑膜中动脉。13例患者中有11例(85%)实现了瘘的完全闭塞。除1例海绵窦dAVF发生Onyx迁移外,无其他并发症。术后3个月改良Rankin量表评分为0分的患者有11例,3分的患者有2例。
经动脉Onyx栓塞可作为dAVF患者的一线治疗选择。然而,由于液体栓塞材料有颅内迁移的风险,海绵窦dAVF应首先尝试经静脉途径。此外,对于难以到达的路径,联合手术血管内治疗可被视为一种有用的选择。