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波多黎各纤维肌痛综合征患者超重/肥胖相关的临床表现

Clinical Manifestations Associated with Overweight/Obesity in Puerto Ricans with Fibromyalgia Syndrome.

作者信息

Fred-Jiménez Ruth M, Arroyo-Ávila Mariangelí, Mayor Ángel M, Ríos Grissel, Vilá Luis M

机构信息

Division of Rheumatology, Department of Medicine, University of Puerto Rico, Medical Sciences Campus, San Juan, PR 00936, USA.

Division of Rheumatology, Department of Medicine, University of Puerto Rico, Medical Sciences Campus, San Juan, PR 00936, USA; Retrovirus Research Center, Department of Internal Medicine, Universidad Central del Caribe School of Medicine, Bayamón, PR 00960, USA.

出版信息

J Obes. 2016;2016:1379289. doi: 10.1155/2016/1379289. Epub 2016 Jan 18.

Abstract

Objective. To determine the clinical manifestations associated with overweight/obesity in Hispanics from Puerto Rico with fibromyalgia syndrome (FMS). Methods. A cross-sectional study was performed in 144 patients with FMS (per American College of Rheumatology (ACR) classification criteria). Sociodemographic features, FMS-related symptoms, tender points (per ACR criteria), comorbidities, and FMS treatment were examined. BMI was calculated and patients were grouped into two categories: BMI ≤ 24.9 kg/m(2) (nonoverweight/obese) and BMI ≥ 25 kg/m(2) (overweight/obese). Bivariate and multivariate analyses were used to evaluate differences between the study groups. Results. The mean (standard deviation (SD)) age of patients was 50.2 (9.9) years; 95.1% were females and 75.7% were overweight/obese. In the bivariate analysis, overweight/obese patients were more likely to have self-reported memory impairment, anxiety, shortness of breath, and urinary frequency than nonoverweight/obese patients. In addition, the tender point count was higher in the overweight/obese group. In the logistic regression analyses, self-reported memory impairment and urinary frequency differences remained significant after adjusting for confounding variables. Conclusion. In this population of Puerto Ricans with FMS, overweight/obese patients experienced more FMS-related manifestations than nonoverweight/obese individuals. However, prospective studies are needed to confirm these associations and to elucidate if weight reduction interventions could favorably impact the severity of FMS.

摘要

目的。确定来自波多黎各的患有纤维肌痛综合征(FMS)的西班牙裔超重/肥胖患者的临床表现。方法。对144例符合美国风湿病学会(ACR)分类标准的FMS患者进行了一项横断面研究。研究了社会人口统计学特征、FMS相关症状、压痛点(根据ACR标准)、合并症以及FMS治疗情况。计算体重指数(BMI)并将患者分为两类:BMI≤24.9 kg/m²(非超重/肥胖)和BMI≥25 kg/m²(超重/肥胖)。采用双变量和多变量分析来评估研究组之间的差异。结果。患者的平均(标准差(SD))年龄为50.2(9.9)岁;95.1%为女性,75.7%超重/肥胖。在双变量分析中,超重/肥胖患者比非超重/肥胖患者更有可能自我报告有记忆障碍、焦虑、呼吸急促和尿频。此外,超重/肥胖组的压痛点计数更高。在逻辑回归分析中,调整混杂变量后,自我报告的记忆障碍和尿频差异仍然显著。结论。在这群患有FMS的波多黎各人中,超重/肥胖患者比非超重/肥胖个体经历更多与FMS相关的表现。然而,需要前瞻性研究来证实这些关联,并阐明减重干预措施是否能对FMS的严重程度产生有利影响。

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