Lu William, Krellman Jason W, Dijkers Marcel P
Rusk Rehabilitation, New York University Langone Medical Center, New York, NY, USA.
Department of Rehabilitation Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
NeuroRehabilitation. 2016;38(1):59-69. doi: 10.3233/NRE-151296.
Individuals with traumatic brain injury (TBI) often develop sleep disorders post-injury. The most common one is insomnia, which can exacerbate other post-injury symptoms, including fatigue, impaired cognition, depression, anxiety, and pain. Cognitive Behavioral Therapy for Insomnia (CBT-I) is a manualized treatment that effectively treats insomnia with secondary effects on cognition, mood, and pain in various populations.
This paper reviews the use of CBT-I for three participants with TBI of different severities.
Pre- and post-treatment assessments of insomnia, fatigue, depression, anxiety, and pain were conducted. Mood was further assessed at follow-up. Minimal clinically important difference (MCID) scores derived from the research literature were used to establish clinically meaningful symptom improvement on self-report questionnaires.
The reduction in insomnia severity scores for all three participants were not large enough to be considered a clinically significant improvement following CBT-I, although trends toward improvement were observed. However, all participants showed clinically significant reductions in anxiety at post-treatment; the effects persisted for 2 participants at follow-up. Reductions in depression symptoms were observed for 2 participants at post-treatment, and treatment effects persisted for 1 participant at follow-up. One participant endorsed clinically significant improvements in fatigue and pain severity.
We conclude that CBT-I may provide secondary benefits for symptoms commonly experienced by individuals with TBI, especially mood disturbances.
创伤性脑损伤(TBI)患者受伤后常出现睡眠障碍。最常见的是失眠,它会加重其他受伤后的症状,包括疲劳、认知障碍、抑郁、焦虑和疼痛。失眠的认知行为疗法(CBT-I)是一种标准化治疗方法,能有效治疗失眠,并对不同人群的认知、情绪和疼痛产生次要影响。
本文回顾了CBT-I对三名不同严重程度的TBI患者的应用情况。
对失眠、疲劳、抑郁、焦虑和疼痛进行治疗前和治疗后的评估。在随访时进一步评估情绪。使用从研究文献中得出的最小临床重要差异(MCID)分数来确定自我报告问卷上具有临床意义的症状改善情况。
尽管观察到有改善趋势,但三名参与者的失眠严重程度评分降低幅度均不足以被认为是CBT-I治疗后具有临床意义的改善。然而,所有参与者在治疗后焦虑都有临床显著降低;两名参与者在随访时效果持续存在。两名参与者在治疗后抑郁症状有所减轻,一名参与者在随访时治疗效果持续存在。一名参与者在疲劳和疼痛严重程度方面有临床显著改善。
我们得出结论,CBT-I可能对TBI患者常见的症状产生次要益处,尤其是情绪障碍。