Kanodia K V, Vanikar A V, Patel R D, Suthar K S, Trivedi H L
Professor, Department of Pathology, Laboratory Medicine, Transfusion Services and Immunohematology, G.R. Doshi and K.M. Mehta Institute of Kidney Diseases & Research Centre and Dr. H.L. Trivedi Institute of Transplantation Sciences , Civil Hospital Campus, Asarwa, Ahmedabad, India .
Professor and Head, Department of Pathology, Laboratory Medicine, Transfusion Services and Immunohematology, G.R. Doshi and K.M. Mehta Institute of Kidney Diseases & Research Centre and Dr. H.L. Trivedi Institute of Transplantation Sciences , Civil Hospital Campus, Asarwa, Ahmedabad, India .
J Clin Diagn Res. 2016 Jan;10(1):ED01-2. doi: 10.7860/JCDR/2016/14191.6970. Epub 2016 Jan 1.
Tuberculosis of kidney and urinary tract is caused by members of the Mycobacterium tuberculosis complex. Kidney is usually infected by haematogenous spread of bacilli from focus of infection in the lungs. Glomerular involvement in tuberculosis presenting as a rapidly progressive glomerulonephritis is a rare entity. We report a rare case of crescentic glomerulonephritis associated with pulmonary tuberculosis in a 26-year-old man. Patient was treated with corticosteroids, haemodialysis, intravenous immunoglobulin and four cycles of plasmapheresis. He did not respond to 4-drug anti-tuberculosis treatment for renal pathology and was switched over to maintenance haemodialysis. However, he responded to pulmonary TB.
肾脏和泌尿系统结核由结核分枝杆菌复合群成员引起。肾脏通常通过杆菌从肺部感染灶经血行播散而被感染。以快速进展性肾小球肾炎形式出现的肾小球受累在结核病中是一种罕见情况。我们报告一例26岁男性新月体性肾小球肾炎合并肺结核的罕见病例。患者接受了皮质类固醇、血液透析、静脉注射免疫球蛋白和四个周期的血浆置换治疗。他对针对肾脏病变的四联抗结核治疗无反应,转而接受维持性血液透析。然而,他对肺结核治疗有反应。