Muthiah Thilaka, Moni Amarnath, Mathews Lailu, Balaji Sudarshan
Department of Anaesthesiology and Critical Care, Chettinad Hospital and Research Institute, Kelambakkam, 603103, India.
J Clin Anesth. 2016 Mar;29:30-2. doi: 10.1016/j.jclinane.2015.10.011. Epub 2016 Feb 2.
Dexmedetomidine is widely used for procedural sedation because of its unique combination of sedation, analgesia, and anxiolysis with minimal respiratory depression. Transient hypertension has been reported during the use of dexmedetomidine which is usually benign and is taken over by the hypotensive response on continuing the infusion. We report a case of hypertensive crisis following dexmedetomidine infusion used for procedural sedation, necessitating discontinuation of the infusion and treatment of hypertension. The dilemmas involved in treating hypertension caused by dexmedetomidine are discussed.
右美托咪定因其镇静、镇痛和抗焦虑作用独特且呼吸抑制轻微，而被广泛用于操作过程中的镇静。使用右美托咪定期间曾有短暂性高血压的报道，这种情况通常是良性的，持续输注时会被降压反应取代。我们报告1例在用于操作镇静的右美托咪定输注后发生高血压危象的病例，需要停止输注并治疗高血压。文中讨论了治疗右美托咪定所致高血压所涉及的难题。
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