Sridhar Jayanth, Chang Jonathan S, Aziz Hassan A, Erickson Benjamin P
Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida, USA.
Oman J Ophthalmol. 2015 Sep-Dec;8(3):198-9. doi: 10.4103/0974-620X.169893.
Marfan syndrome (MFS) is associated with abnormal fibrillin development that can cause morbidity and mortality. A case of acute onset hypotony due to sclerotomy wound dehiscence 13 years after 20-gauge pars plana vitrectomy and lensectomy is reported in a patient with MFS. Slit lamp examination revealed a leaking sclerotomy wound and intraoperatively the source was noted to be the prior sclerotomy site. On postoperative follow-up, the patient's vision returned to baseline, and intraocular pressure normalized. Twenty-gauge sclerotomy wound dehiscence may occur years after surgery, especially in patients with abnormal collagen as in MFS.
马凡综合征(MFS)与原纤维蛋白发育异常有关,可导致发病和死亡。本文报告了一例马凡综合征患者,在20G玻璃体切割术联合晶状体切除术后13年,因巩膜切开伤口裂开导致急性低眼压。裂隙灯检查发现巩膜切开伤口渗漏,术中发现渗漏源为先前的巩膜切开部位。术后随访时,患者视力恢复至基线水平,眼压恢复正常。20G巩膜切开伤口裂开可能在手术后数年发生,尤其是在像马凡综合征患者这样存在胶原异常的患者中。