Suppr超能文献

肿瘤整形保乳手术与肿瘤学结局:系统评价

Oncoplastic breast conserving surgery and oncological outcome: Systematic review.

作者信息

Yiannakopoulou E C, Mathelin C

机构信息

Department of Medical Laboratories, Faculty of Health and Caring Professions, Technological Educational Institute of Athens, Athens, Greece.

Pôle de gynécologie-obstétrique, hôpital de Hautepierre, hôpitaux universitaires de Strasbourg, avenue Molière, 67200 Strasbourg Cedex, France.

出版信息

Eur J Surg Oncol. 2016 May;42(5):625-30. doi: 10.1016/j.ejso.2016.02.002. Epub 2016 Feb 10.

Abstract

UNLABELLED

Oncoplastic surgery consists a new approach for extending breast conserving surgery possibilities This manuscript aimed to systematically review data on the oncological outcome of oncoplastic breast surgery. Electronic databases were searched with the appropriate search term up to and included April 2013.

INCLUSION CRITERIA

full publications including at least 10 patients and providing evidence on at least one of the following outcomes: margin involvement, local recurrence, metastatic disease, death number. Forty studies including 2830 patients, met inclusion criteria; twenty one studies investigated volume displacement techniques; fifteen studies investigated volume replacement techniques; four studies presented data on various oncoplastic techniques. Study quality was low. The majority of studies were observational studies. The length of follow up was relatively short, with only two studies reporting a median duration longer than 60 months. Only seven studies including more than 100 patients. There was great variation in the frequency of margin involvement ranging between 0% and 36% of patients. Local recurrence was observed in 0-10.8% of patients. Distant metastasis was observed in 0-18.9% of patients. In conclusion, long term oncological outcome of oncoplastic surgery for breast cancer is not adequately investigated. Further research efforts should focus on Level I evidence on oncological outcome of oncoplastic surgery.

摘要

未标注

肿瘤整形手术是一种拓展保乳手术可能性的新方法。本手稿旨在系统回顾肿瘤整形乳房手术肿瘤学结局的数据。截至2013年4月,使用适当的检索词对电子数据库进行了检索,检索范围包括该时间点。

纳入标准

完整出版物,包括至少10例患者,并提供以下至少一项结局的证据:切缘受累、局部复发、转移性疾病、死亡人数。40项研究(包括2830例患者)符合纳入标准;21项研究调查了容积移位技术;15项研究调查了容积替代技术;4项研究提供了各种肿瘤整形技术的数据。研究质量较低。大多数研究为观察性研究。随访时间相对较短,只有两项研究报告的中位持续时间超过60个月。只有7项研究纳入的患者超过100例。切缘受累频率差异很大,患者比例在0%至36%之间。0-10.8%的患者观察到局部复发。0-18.9%的患者观察到远处转移。总之,乳腺癌肿瘤整形手术的长期肿瘤学结局尚未得到充分研究。进一步的研究应聚焦于肿瘤整形手术肿瘤学结局的一级证据。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验