Fengfeng Guo, Xiaobo Yu, Bo Pan, Lin Lin, Haiyue Jiang
Zhonghua Zheng Xing Wai Ke Za Zhi. 2015 Sep;31(5):327-31.
To explore the incidence, degree, and pattern of rib cartilage calcification in congenital microtia patients, in order to provide reference for harvesting the rib cartilage, sculpturing cartilage framework.
From Jun. 2013 to Nov. 2014, 383 patients (age range, 6-45 years) underwent CT scans of the chest. 11 patients with bony diseases or traumatic history were excluded. The remaining 372 patients were divided by age into four groups as 6-15, 16-25, 26-35, 36-45 years old. Twenty patients (10 male and 10 female) were selected by the order of patient identification number in each age group, thus selecting a total of 80 patients (40 male and 40 female). Retrospective study of CT scans of the chest in 80 patients and the incidence, degree, and pattern of cartilage calcification of the sixth to eighth ribs were noted. A chi-square test is conducted to test whether there are significant difference between the variables through the SPSS 19.0 software.
Overall, 40.4% (194/480) cartilage was calcified; female patients (47.50%, 114/240) showed higher frequency of calcification than male patients (33.33%, 80/240, P = 0. 025). Calcification rates of all age groups are 1.7% (2/120), 46.7% (56/ 120), 49.2% (59/120), 64.2% (77/120). Calcification rate of 6-15 years group is lowest in all groups (P < 0.05) while other three groups have no statistical significance (P > 0.05). Calcification rates of the sixth and sevent rib cartilage were higher than those of the eighth rib cartilage in all age groups except 6-15 years group, who had a similar rate of all three ribs. Calcification rate of all three rib cartilage was significantly increased with age. Calcification rates of the amle's rib cartilage and the female's in all age groups are 3.3% (2/60) and 0.0% (0/60) (6-15 years): 33.3% (20/60) and 60.0% (36/60) (16-25 years): 40.0% (24/60) and 58.3% (35/60) (26-35 years), 56.7% (34/60) and 71.2% (43/60) (36-45 years). In 6-15 years group calcification rates of male and female had a similar rate, while female's rates were higher than male's rates in other three groups. Male and females mainly had the granular type of calcification [70.0% (56/80), 63.2% (72/114)].
Females who are over 16 years old should pay more attention to the possibility of middle-severe calcification before harvesting rib cartilage. These patients should take CT examination if necessary. In addition, the patients who had previous operation, or traumatic history, rib deformity, or spine deformity should select the CT examination.
探讨先天性小耳畸形患者肋软骨钙化的发生率、程度及模式，为肋软骨切取、软骨支架雕刻提供参考。
2013年6月至2014年11月，383例年龄在6 - 45岁的患者接受胸部CT扫描。排除11例有骨病或外伤史的患者。将其余372例患者按年龄分为6 - 15岁、16 - 25岁、26 - 35岁、36 - 45岁四组。在每个年龄组中按患者识别号顺序选取20例患者（男10例，女10例），共选取80例患者（男40例，女40例）。回顾性分析80例患者胸部CT扫描结果，记录第六至第八肋软骨钙化的发生率、程度及模式。通过SPSS 19.0软件进行卡方检验，以检验各变量之间是否存在显著差异。
总体而言，40.4%（194/480）的软骨发生钙化；女性患者钙化频率（47.50%，114/240）高于男性患者（33.33%，80/240，P = 0.025）。各年龄组钙化率分别为1.7%（2/120）、46.7%（56/120）、49.2%（59/120）、64.2%（77/120）。6 - 15岁组钙化率在所有组中最低（P < 0.05），其他三组无统计学意义（P > 0.05）。除6 - 15岁组三根肋骨钙化率相似外，其他年龄组第六和第七肋软骨钙化率高于第八肋软骨。三根肋软骨钙化率均随年龄显著增加。各年龄组男性和女性肋软骨钙化率分别为：6 - 15岁组3.3%（2/60）和0.0%（0/60）；16 - 25岁组33.3%（20/60）和60.0%（36/60）；26 - 35岁组40.0%（24/60）和58.3%（35/60）；36 - 45岁组56.7%（34/60）和71.2%（43/60）。6 - 15岁组男性和女性钙化率相似，其他三组女性钙化率高于男性。男性和女性主要为颗粒型钙化[70.0%（56/80），63.2%（72/114）]。
16岁以上女性在切取肋软骨前应更关注中重度钙化的可能性。必要时这些患者应进行CT检查。此外，有既往手术史、外伤史、肋骨畸形或脊柱畸形的患者应选择CT检查。
