导管依赖性体循环的杂交姑息治疗
Hybrid Palliation for Ductal-Dependent Systemic Circulation.
作者信息
Evans William N, Galindo Alvaro, Rothman Abraham, Ciccolo Michael L, Carrillo Sergio A, Acherman Ruben J, Mayman Gary A, Cass Kathleen A, Kip Katrinka T, Luna Carlos F, Ludwick Joseph M, Rollins Robert C, Castillo William J, Alexander John A, Restrepo Humberto
机构信息
Children's Heart Center Nevada, 3006 S. Maryland Pkwy Ste. 690, Las Vegas, NV, 89109, USA.
Division of Pediatric Cardiology, Department of Pediatrics, University of Nevada School of Medicine, 2040 W. Charleston Blvd Ste. 402, Las Vegas, NV, 89109, USA.
出版信息
Pediatr Cardiol. 2016 Jun;37(5):868-77. doi: 10.1007/s00246-016-1361-3. Epub 2016 Mar 1.
We reviewed our hybrid palliation experience for 91 neonates, with ductal-dependent systemic circulation, born between August 2007 and October 2015. For analysis, we stratified the 91 patients by a risk factor (RF) score and divided them into three groups: (1) high-risk two-functional ventricles (2V) median RF score of 3 (N = 20); (2) low-risk one-functional ventricle (1V) RF score 0-1 (N = 32); and (3) high-risk 1V RF score ≥2 (N = 39). Midterm survival (median 4 years) by group was: (1) 95 %, (2) 91 %, and (3) 15 %, (p = 0.001). In conclusion, hybrid palliation was associated with excellent midterm results for high-risk 2V and low-risk 1V patients with ductal-dependent systemic circulation. In contrast, high-risk 1V patients had significantly worse outcomes.
我们回顾了2007年8月至2015年10月期间出生的91例患有导管依赖性体循环的新生儿的杂交姑息治疗经验。为了进行分析，我们根据风险因素（RF）评分对91例患者进行分层，并将他们分为三组：（1）高危双功能心室（2V），RF评分中位数为3（N = 20）；（2）低危单功能心室（1V），RF评分为0 - 1（N = 32）；（3）高危1V，RF评分≥2（N = 39）。各组的中期生存率（中位数4年）分别为：（1）95%，（2）91%，（3）15%，（p = 0.001）。总之，杂交姑息治疗对于患有导管依赖性体循环的高危2V和低危1V患者具有良好的中期结果。相比之下，高危1V患者的结局明显更差。
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