Raza Sughra, Mackesy Meaghan M, Winkler Nicole S, Hurwitz Shelley, Birdwell Robyn L
Department of Radiology, Brigham and Women's Hospital, Boston, Massachusetts.
Department of Radiology, Brigham and Women's Hospital, Boston, Massachusetts.
J Am Coll Radiol. 2016 Mar;13(3):310-5. doi: 10.1016/j.jacr.2015.10.025.
The aim of this study was to evaluate the accuracy of visual mammographic breast density assessment and determine if training can improve this assessment, to compare the accuracy of qualitative density assessment before and after training with a quantitative assessment tool, and to evaluate agreement between qualitative and quantitative density assessment methods.
Consecutive screening mammograms performed over a 4-month period were visually assessed by two study breast radiologists (the leads), who selected 200 cases equally distributed among the four BI-RADS density categories. These 200 cases were shown to 20 other breast radiologists (the readers) before and after viewing a training module on visual density assessment. Agreement between reader assessment and lead radiologist assessment was calculated for both reading sessions. Quantitative volumetric density of the 200 mammograms, determined using a commercially available tool, was compared with both sets of reader assessment and with lead radiologist assessment.
Compared with lead radiologist assessment, reader accuracy of breast density assessment increased from 65% before training to 72% after training (odds ratio, 1.41; P < .0001). Training specifically improved assignment to BI-RADS categories 1 (P < .0001) and 4 (P < .10). Compared with quantitative assessment, reader accuracy showed statistically nonsignificant improvement with training (odds ratio, 1.1; P = .26). Substantial agreement between qualitative and quantitative breast density assessment was demonstrated (κ = 0.78).
Training may improve the accuracy of mammographic breast density assessment. Substantial agreement between qualitative and quantitative breast density assessment exists.
本研究旨在评估乳腺钼靶X线摄影中乳腺密度视觉评估的准确性,并确定培训是否能改善这种评估,比较培训前后定性密度评估与定量评估工具的准确性,以及评估定性和定量密度评估方法之间的一致性。
在4个月期间进行的连续筛查乳腺钼靶X线片由两位研究乳腺放射科医生(负责人)进行视觉评估,他们选择了200例在四个BI-RADS密度类别中均匀分布的病例。在观看关于视觉密度评估的培训模块之前和之后,将这200例病例展示给另外20位乳腺放射科医生(阅片者)。计算两个阅片阶段阅片者评估与放射科负责人评估之间的一致性。使用市售工具确定的200例乳腺钼靶X线片的定量体积密度与两组阅片者评估以及放射科负责人评估进行比较。
与放射科负责人评估相比,阅片者乳腺密度评估的准确性从培训前的65%提高到培训后的72%(优势比,1.41;P <.0001)。培训特别改善了BI-RADS 1类(P <.0001)和4类(P <.10)的分类。与定量评估相比,阅片者的准确性在培训后显示出统计学上无显著改善(优势比,1.1;P =.26)。定性和定量乳腺密度评估之间显示出高度一致性(κ = 0.78)。
培训可能会提高乳腺钼靶X线摄影中乳腺密度评估的准确性。定性和定量乳腺密度评估之间存在高度一致性。