Chao N J, Blume K G
West J Med. 1989 Dec;151(6):638-43.
Major progress in experimental and clinical research has made allogeneic bone marrow transplantation a highly effective therapy for a variety of malignant and nonmalignant diseases. Allogeneic bone marrow transplantation from histocompatible donors is now the therapy of choice for some of these disorders. We review in part I the history, technical approach, complications, and the results achievable with this therapeutic approach. Further experimentation and future goals are also discussed.
实验研究和临床研究取得的重大进展已使异基因骨髓移植成为治疗多种恶性和非恶性疾病的高效疗法。来自组织相容性供体的异基因骨髓移植现已成为其中一些疾病的首选治疗方法。在第一部分中,我们回顾了这种治疗方法的历史、技术手段、并发症以及可取得的治疗效果。还讨论了进一步的实验和未来目标。