Demailly P, Lehrer M, Kretz G
Hôpital Saint-Joseph, Paris.
J Fr Ophtalmol. 1989;12(3):183-9.
A prospective randomised study was undertaken on sixty eyes, thirty five patients, (27 women, 8 men) followed in the Saint-Joseph hospital of Paris, with low tension glaucoma (LTG). The thirty five patients were selected at random and had either an argon laser trabeculoplasty (ALT) or received only vascular medications (medial). The first group (ALT) included 29 eyes. The second group (medical) included 31 eyes. The two groups were comparable: mean age, men/women distribution, mean intraocular pressure, mean C/D ratio, mean total visual capability (TVC) with the friedmann analyser. The mean follow up for the two groups was seven years. Nevertheless for the ALT group the mean follow up after ALT was four years. We compared for the two groups: --the aspect of the mean intraocular pressure (IOP) curve with time, --the evolution gradient of visual capabilities with time. For the ALT group we compared: --the mean IOP and 24 hours diurnal curves before and after laser treatment and the evolution gradient of visual capabilities before and after laser treatment. The introduction of ALT in the treatment of LTG had neither tonometric effect nor effect on the slope of visual field damage. We concluded that ALT is not recommended in LTG, but not that the IOP should not be reduced in this form of glaucoma.
对巴黎圣约瑟夫医院收治的35例(27名女性,8名男性)低眼压性青光眼(LTG)患者的60只眼睛进行了一项前瞻性随机研究。35例患者被随机选取,一部分接受氩激光小梁成形术(ALT),另一部分仅接受血管药物治疗(药物治疗组)。第一组(ALT组)包括29只眼睛。第二组(药物治疗组)包括31只眼睛。两组具有可比性:平均年龄、男女分布、平均眼压、平均杯盘比、使用弗里德曼分析仪测得的平均总视觉能力(TVC)。两组的平均随访时间为7年。然而,ALT组在ALT术后的平均随访时间为4年。我们比较了两组:——平均眼压(IOP)随时间变化的曲线情况,——视觉能力随时间的演变梯度。对于ALT组,我们比较了:——激光治疗前后的平均IOP和24小时昼夜曲线,以及激光治疗前后视觉能力的演变梯度。ALT用于治疗LTG既没有眼压降低作用,也对视野损害斜率没有影响。我们得出结论,不建议在LTG中使用ALT,但并非不建议以这种形式降低青光眼的眼压。