Kenyon Katharine, Zedek Daniel, Sayed Christopher
School of Medicine, The University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Department of Dermatology, The University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
J Cutan Pathol. 2016 Jul;43(7):609-612. doi: 10.1111/cup.12703. Epub 2016 Apr 7.
Aplasia cutis congenita and cutaneous meningeal heterotopia are both rare congenital conditions that most commonly occur on the scalp and may appear clinically and histologically similar. A subtype of aplasia cutis congenita, membranous aplasia cutis congenita, and cutaneous meningeal heterotopia are both proposed to result from neural tube closure errors. However, neither non-membranous nor membranous aplasia cutis congenita are known to occur together with cutaneous meningeal heterotopia in the same lesion. We report the incidental finding of cutaneous meningeal heterotopia within a lesion of aplasia cutis congenita.
先天性皮肤发育不全和皮肤脑膜异位均为罕见的先天性疾病,最常发生于头皮,在临床和组织学上可能表现相似。先天性皮肤发育不全的一个亚型,即膜性先天性皮肤发育不全,以及皮肤脑膜异位均被认为是由神经管闭合错误导致的。然而,非膜性和膜性先天性皮肤发育不全均未被发现与皮肤脑膜异位在同一病变中同时出现。我们报告了在先天性皮肤发育不全病变中偶然发现皮肤脑膜异位的情况。