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老年住院患者潜在不适当用药(PIMs):患病率、对住院的影响及继续用药理由的记录

Potentially inappropriate medications (PIMs) in older hospital in-patients: Prevalence, contribution to hospital admission and documentation of rationale for continuation.

作者信息

Ní Chróinín Danielle, Neto Hugo M, Xiao Diane, Sandhu Anmol, Brazel Carly, Farnham Nell, Perram Jacinta, Roach Timothy S, Sutherland Emily, Day Ric, Beveridge Alexander

机构信息

Department of Geriatric Medicine, St. Vincent's Hospital, Sydney, New South Wales, Australia.

Department of Geriatric Medicine, Liverpool Hospital, Sydney, New South Wales, Australia.

出版信息

Australas J Ageing. 2016 Dec;35(4):262-265. doi: 10.1111/ajag.12312. Epub 2016 Mar 11.

Abstract

AIM

To establish prevalence, sequelae and documentation of potentially inappropriate medication (PIM) use in older hospital in-patients.

METHODS

Notes of all patients ≥65 years old, admitted to our tertiary teaching hospital (January 2013), were retrospectively reviewed, and the Screening Tool of Older Persons' potentially inappropriate Prescriptions applied.

RESULTS

Amongst 534 patients, 54.8% (284) were on ≥1 PIM at admission, 26.8% on multiple; 60.8% were discharged on a PIM. Six percent of all admissions were potentially attributable to a PIM; falls associated with risk therapies were commonest (23/30), and often (65.2%) associated with serious injury. Pre-specified subgroup analysis (n = 100) identified 101 PIMs-at-discharge amongst 47 patients. In 82.2%, a clinical rationale for continued prescription was documented, with this communicated to the GP by letter in 71.1%.

CONCLUSION

PIMs were common, and contributed to admission and injury. Hospitalisation provides an opportunity for medication rationalisation, and documentation of rationale for any PIM use.

摘要

目的

确定老年住院患者中潜在不适当用药(PIM)的发生率、后遗症及记录情况。

方法

回顾性分析2013年1月入住我院三级教学医院的所有65岁及以上患者的病历,并应用老年人潜在不适当处方筛查工具。

结果

在534例患者中,54.8%(284例)入院时使用≥1种PIM,26.8%使用多种;60.8%出院时仍在使用PIM。所有入院病例中有6%可能归因于PIM;与风险治疗相关的跌倒最为常见(23/30),且常(65.2%)与严重损伤相关。预先设定的亚组分析(n = 100)在47例患者中确定了101种出院时的PIM。在82.2%的病例中,记录了继续用药的临床理由,其中71.1%通过信函告知了全科医生。

结论

PIM很常见,且与入院和损伤有关。住院治疗为药物合理使用及记录任何PIM使用理由提供了机会。

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