den Harder Annemarie M, de Heer Linda M, Meijer Ronald C A, Das Marco, Krestin Gabriel P, Maessen Jos G, Bogers Ad J J C, de Jong Pim A, Leiner Tim, Budde Ricardo P J
Department of Radiology, University Medical Center, P.O. Box 85000, 3508 GA Utrecht, The Netherlands.
Department of Cardiothoracic Surgery, University Medical Center, P.O. Box 85000, 3508 GA Utrecht, The Netherlands.
Eur J Radiol. 2016 Apr;85(4):744-50. doi: 10.1016/j.ejrad.2016.01.003. Epub 2016 Jan 14.
To investigate whether preoperative chest computed tomography (CT) decreases postoperative mortality and stroke rate in cardiac surgery by detection of calcifications and visualization of postoperative anatomy in redo cardiac surgery which can be used to optimize the surgical approach.
The PubMed, EMBASE and Cochrane databases were searched and articles concerning preoperative CT in cardiac surgery were included. Articles not reporting mortality, stroke rate or change in surgical approach were excluded. Studies concerning primary cardiac surgery as well as articles concerning redo cardiac surgery were both included.
Eighteen studies were included (n=4057 patients) in which 2584 patients received a preoperative CT. Seven articles (n=1754 patients) concerned primary surgery and eleven articles (n=2303 patients) concerned redo cardiac surgery. None of the studies was randomized but 8 studies provided a comparison to a control group. Stroke rate decreased with 77-96% (primary surgery) and 18-100% (redo surgery) in patients receiving a preoperative CT. Mortality decreased up to 66% in studies investigating primary surgery while the effect on mortality in redo surgery varied widely. Change in surgical approach based on CT-findings consisted of choosing a different cannulation site, opting for off-pump surgery and cancellation of surgery.
Current evidence suggests that preoperative CT imaging may lead to decreased stroke and mortality rate in patients undergoing primary cardiac surgery by optimizing surgical approach. In patients undergoing redo cardiac surgery stroke rate is also decreased but the effect on mortality is unclear. However, evidence is weak and included studies were of moderate quality.
研究术前胸部计算机断层扫描(CT)能否通过检测钙化以及显示再次心脏手术术后解剖结构来优化手术入路,从而降低心脏手术的术后死亡率和中风发生率。
检索了PubMed、EMBASE和Cochrane数据库,纳入了有关心脏手术术前CT的文章。排除未报告死亡率、中风发生率或手术入路变化的文章。纳入了有关初次心脏手术的研究以及有关再次心脏手术的文章。
共纳入18项研究(n = 4057例患者),其中2584例患者接受了术前CT检查。7篇文章(n = 1754例患者)涉及初次手术,11篇文章(n = 2303例患者)涉及再次心脏手术。所有研究均非随机对照研究,但有8项研究提供了与对照组的比较。接受术前CT检查的患者中风发生率在初次手术中降低了77 - 96%,在再次手术中降低了18 - 100%。在研究初次手术的研究中,死亡率降低了66%,而再次手术中对死亡率的影响差异很大。基于CT检查结果的手术入路改变包括选择不同的插管部位、选择非体外循环手术和取消手术。
目前的证据表明,术前CT成像可能通过优化手术入路降低初次心脏手术患者的中风和死亡率。在再次心脏手术患者中,中风发生率也降低了,但对死亡率的影响尚不清楚。然而,证据薄弱,纳入的研究质量中等。