Rossignol Patrick
Inserm U1116, centre d'investigations cliniques-plurithématique 14-33, 4, rue du Morvan, 54500 Vandœuvre-lès-Nancy, France; Institut lorrain du cœur et des vaisseaux Louis-Mathieu, CHRU de Nancy, 4, rue du Morvan, 54500 Vandœuvre-lès-Nancy, France; Université de Lorraine, 34, cours Léopold, 54000 Nancy, France; Association Lorraine de traitement de l'insuffisance rénale (Altir), 4, rue du Morvan, 54511 Vandœuvre-lès-Nancy, France; F-CRIN INI-CRCT (Cardiovascular and renal clinical trialists), 4, rue du Morvan, 54500 Vandœuvre-lès-Nancy, France.
Nephrol Ther. 2016 Apr;12 Suppl 1:S133-4. doi: 10.1016/j.nephro.2016.01.003. Epub 2016 Mar 10.
The autonomic nervous system plays a pivotal role in the development of hypertension and organ damage complicating hypertension. The US company CVRx developed medical devices (first generation Rheos™ and second generation Neo™) aimed to electronically activate baroreceptors, which signal the brain to orchestrate a multisystemic response to address chronic diseases such as hypertension and heart failure. This review presents available clinical trial data on carotid barostimulation in the treatment of resistant hypertension.