Grishkina M N, Guliaeva N V, Akzhigitov R G, Gersamia A G, Menshikova A A, Freiman S V, Guekht A B
Moscow Research and Clinical Center for Neuropsychiatry, Moscow.
Moscow Research and Clinical Center for Neuropsychiatry, Moscow; Institute of Higher Nervous Activity and Neurophysiology, Russian Academy of Sciences, Moscow.
Zh Nevrol Psikhiatr Im S S Korsakova. 2015;115(12):169-176. doi: 10.17116/jnevro2015115112169-176.
There is evidence that not only severe stressful events, but also common low-threat events, in particular chronic ones, may cause or provoke some mental disorders. The literature data on the degree of pathogenicity of stress factors are insufficient. Authors attempted to summarize the established facts in the following aspects: current conceptions on the physiology and pathology of stress in the frames of the problem of psychosomatic disorders, deprivation in childhood, neurobiological consequences of childhood stress, psychiatric consequences of stress in childhood. Authors believe that this problem demands further investigation to find possible predictors of mental disorders in patients who had experienced stressful life events in childhood.
有证据表明,不仅严重的应激事件,而且常见的低威胁事件,尤其是慢性事件,都可能导致或引发一些精神障碍。关于应激因素致病性程度的文献数据并不充分。作者试图从以下几个方面总结已确定的事实:心身疾病问题框架下应激的生理学和病理学的当前概念、童年期剥夺、童年期应激的神经生物学后果、童年期应激的精神科后果。作者认为,这个问题需要进一步研究,以找到童年期经历过应激生活事件的患者精神障碍的可能预测因素。