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产后母亲抑郁的神经生物学影响:预防与干预方法

The Neurobiological Impact of Postpartum Maternal Depression: Prevention and Intervention Approaches.

作者信息

Drury Stacy S, Scaramella Laura, Zeanah Charles H

机构信息

Department of Psychiatry and Behavioral Sciences, Tulane University, 1430 Tulane avenue, #8055, New Orleans, LA 70112, USA.

Department of Psychology, The University of New Orleans, 2000 Lakeshore Drive, New Orleans, LA 70148, USA.

出版信息

Child Adolesc Psychiatr Clin N Am. 2016 Apr;25(2):179-200. doi: 10.1016/j.chc.2015.11.001. Epub 2016 Jan 11.

Abstract

The lasting negative impact of postpartum depression (PPD) on offspring is well established. PPD seems to have an impact on neurobiological pathways linked to socioemotional regulation, cognitive and executive function, and physiologic stress response systems. This review focus on examining the current state of research defining the effect of universal, selected, and indicated interventions for PPD on infant neurodevelopment. Given the established lasting, and potentially intergenerational, negative implications of maternal depression, enhanced efforts targeting increased identification and early intervention approaches for PPD that have an impact on health outcomes in both infants and mothers represent a critical public health concern.

摘要

产后抑郁症(PPD)对后代的长期负面影响已得到充分证实。PPD似乎会对与社会情感调节、认知和执行功能以及生理应激反应系统相关的神经生物学途径产生影响。本综述着重探讨界定针对PPD的普遍、特定和指示性干预措施对婴儿神经发育影响的研究现状。鉴于母亲抑郁已确定的长期且可能具有代际影响的负面后果,加大力度以提高对PPD的识别率并采用对婴儿和母亲的健康结局均有影响的早期干预方法,是一个至关重要的公共卫生问题。

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