Numerical analysis of corneal curvature dynamics based on Corvis tonometer images.

The paper presents numerical analysis of corneal curvature distribution, based on Corvis ST images. It was shown that a new approach to analysis of corneal curvature from tonometer images enables a better description and understanding of processes during fast corneal deformation. Ten healthy volunteers participated in nine repeated measurements on one eye. 90 sequences of images were processed with software written in Matlab, with the use of the Image Processing Toolbox. Time-spatial distribution of the local curvature distribution of the corneal profile was obtained for each and every measurement. Some new curvature parameters were proposed and analyzed. A high repeatability for individual subjects was obtained for the proposed parameters. For four of these new parameters, the ICC coefficients were higher than 0.85. The ICC value for the calculated curvature of the cornea before deformation reaches 0.989. Such high repeatability of the proposed new parameters can be useful in examination and differentiation of corneas due to their geometrical and biomechanical properties.