Ohara Yoshiko, Toyonaga Takashi, Tanabe Akiko, Takihara Hiroshi, Baba Shinichi, Inoue Taro, Ono Wataru, Kawara Fumiaki, Tanaka Shinwa, Azuma Takeshi
Division of Gastroenterology, Department of Internal Medicine, Graduate School of Medicine, Kobe University, Kobe, Japan.
Department of Endoscopy, Kobe University Hospital, 7-5-1 Kusunoki-cho, Chuo-ku, Kobe, Japan.
Clin J Gastroenterol. 2016 Apr;9(2):63-7. doi: 10.1007/s12328-016-0640-0. Epub 2016 Mar 22.
A 75-year-old female underwent esophagogastroduodenoscopy, revealing a widely spreading tumor occupying the anterior wall, lesser curvature, and posterior wall of the antrum and lower body. Endoscopic submucosal dissection was performed and resulted in more than five-sixths circumferential antral mucosal resection. One month later, she complained of nausea, vomiting, and abdominal distention. Endoscopy showed residual food in the stomach and deformation of the antrum with traction toward the contracted scar in the lesser curvature. The pyloric ring could not be seen from the antrum although the endoscope was able to pass easily beyond the area of deformation and the pyloric ring was intact. Despite repeated endoscopic balloon dilations, the patient's symptoms remained refractory. The problem was speculated to be not due to any potential stricture but to antrum deformation resulting from the traction force toward the healing ulcer. We hypothesized that an additional countertraction force opposite the previous ESD site might resolve the problem, and ESD of approximately 2.5 cm size was performed in the greater curvature of the antrum. Along with development of a scar, traction toward the greater curvature was added, and the pyloric ring could be observed on repeat esophagogastroduodenoscopy. The symptoms were also gradually ameliorated. Afterwards, the endoscopic findings have now been unchanged during 7 years of follow-up.
一名75岁女性接受了食管胃十二指肠镜检查,发现一个广泛扩散的肿瘤占据了胃窦和胃体的前壁、小弯和后壁。进行了内镜下黏膜剥离术,导致胃窦黏膜切除超过六分之五周。一个月后,她出现恶心、呕吐和腹胀症状。内镜检查显示胃内有残留食物,胃窦变形,向小弯处的收缩瘢痕牵拉。尽管内镜能够轻松通过变形区域且幽门环完整,但从胃窦看不到幽门环。尽管反复进行内镜球囊扩张,患者的症状仍难以缓解。推测问题并非由于任何潜在的狭窄,而是由于向愈合溃疡的牵引力导致胃窦变形。我们假设在与先前内镜下黏膜剥离术部位相反的方向施加额外的反向牵引力可能解决问题,并在胃窦大弯处进行了约2.5厘米大小的内镜下黏膜剥离术。随着瘢痕形成,增加了向大弯的牵引力,再次进行食管胃十二指肠镜检查时可以观察到幽门环。症状也逐渐改善。此后,在7年的随访期间内镜检查结果未再改变。