Kim Jeong-Ki, Nam Jeong-Hyun, Lyoo Kwang-Soo, Moon Hyoungjoon, Na Woonsung, Song Eun-Jung, Yeom Minjoo, Shim Sang-Mu, Jeong Dae Gwin, An Dong-Jun, Kang Bo-Kyu, Song Daesub
Department of Pharmacy, College of Pharmacy, Korea University, Sejong 30019, Republic of Korea.
Korea Zoonosis Research Institute, Chonbuk National University, Iksan 54531, Republic of Korea.
J Microbiol Biotechnol. 2016 Jun 28;26(6):1109-14. doi: 10.4014/jmb.1511.11047.
H3N2 canine influenza virus emerged in South Korea in 2007 and subsequently spread to China and Thailand, causing epidemic or endemic respiratory diseases in dogs. Through intermammalian species transmission, the virus has also infected cats. However, no direct evidence of significant genetic evolution has been reported since its first emergence. Here, we describe in depth the genetic and molecular characteristics of the ancestral strain (i.e., the first virus isolate from South Korea) of the H3N2 canine influenza virus currently circulating in East Asia.
H3N2犬流感病毒于2007年在韩国出现,随后传播到中国和泰国,在犬类中引发流行性或地方性呼吸道疾病。通过跨物种传播,该病毒也感染了猫。然而,自首次出现以来,尚未有重大基因进化的直接证据报道。在此,我们深入描述了目前在东亚流行的H3N2犬流感病毒原始毒株(即从韩国分离出的第一株病毒)的基因和分子特征。