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针对假设病例的儿科医生咳嗽和感冒药物处方——一项横断面多中心研究。

Pediatrician's cough and cold medication prescription for hypothetical cases - A cross-sectional multi-centric study.

作者信息

Chandelia Sudha, Dhankar Mukesh, Salhan Meetu

机构信息

Department of Pediatrics, Critical Care Division, Pt. B.D. Sharma Post Graduate Institute of Medical Sciences, Rohtak, Haryana, India.

Department of Pediatrics, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, India.

出版信息

Saudi Pharm J. 2016 Mar;24(2):176-81. doi: 10.1016/j.jsps.2015.02.011. Epub 2015 Mar 19.

Abstract

BACKGROUND

Concerns over inappropriate use of cough and cold medication (CCM) in children have been raised. In addition to being ineffective, these are now considered toxic for young children. Despite this fact studies from some regions have shown high use of these medications by physicians. However data on pediatricians and from India are negligible.

AIM

To study the burden and patterns of cough and cold medications use by pediatricians for hypothetical cases.

METHODS

In this cross-sectional study; 172 pediatricians of various hospitals of Delhi and Haryana were enrolled from February 15 to March 15, 2012. They were contacted personally by authors and asked to write their prescriptions for two hypothetical case scenarios [having cough and cold] of two different age groups; (1) less than 2 years and (2) 2-5 years. We made two categories as recommendations exist for children less than 2 years while recommendations for the second category are underway. RESULTS were summarized as percentages, counts and; presented in tables and figures. Chi square test was used to establish association between categorical variables of subgroups.

RESULTS

Response rate was 93%. The most used CCM was antihistaminics (82%) and systemic sympathomimetics (48%). The use of CCM was significantly less in teaching hospitals as compared to non-teaching (77% vs. 95%; p-value - 0.025). However there was no statistical difference in the practice of post graduates and more senior pediatricians (p value-0.895). No difference in CCM use in two age groups {(82% (less than 2 years) vs. 85% (2-5 years); p-value - 0.531} was observed.

CONCLUSION

Overall use of CCM is still high irrespective of patient age, pediatrician's seniority or hospital setting. Efforts should be made to create awareness among the pediatricians regarding cautious use of these medications.

摘要

背景

人们对儿童咳嗽和感冒药(CCM)的不当使用表示担忧。这些药物不仅无效,现在还被认为对幼儿有毒性。尽管如此,一些地区的研究表明医生对这些药物的使用频率很高。然而,来自印度儿科医生的数据却少之又少。

目的

研究儿科医生针对假设病例使用咳嗽和感冒药的负担及模式。

方法

在这项横断面研究中,于2012年2月15日至3月15日招募了德里和哈里亚纳邦各医院的172名儿科医生。作者亲自与他们联系,要求他们为两个不同年龄组的两种假设病例情况(患有咳嗽和感冒)开出处方;(1)2岁以下和(2)2至5岁。由于针对2岁以下儿童已有用药建议,而针对第二类儿童的用药建议正在制定中,我们将其分为两类。结果以百分比、计数形式总结,并呈现在表格和图表中。采用卡方检验来确定亚组分类变量之间的关联。

结果

回复率为93%。最常用的CCM是抗组胺药(82%)和全身性拟交感神经药(48%)。与非教学医院相比,教学医院CCM的使用显著较少(77%对95%;p值 - 0.025)。然而,研究生和更资深的儿科医生在用药习惯上没有统计学差异(p值 - 0.895)。在两个年龄组中CCM的使用没有差异{(2岁以下为82%,2至5岁为85%;p值 - 0.531)}。

结论

无论患者年龄、儿科医生资历或医院环境如何,CCM的总体使用仍然很高。应努力提高儿科医生对谨慎使用这些药物的认识。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e364/4792892/fe5120a30527/gr3.jpg

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