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关于“自闭症谱系障碍患者及其一级亲属的血小板研究”的评论

Commentary on "Platelet Studies in Autism Spectrum Disorder Patients and First-Degree Relatives".

作者信息

Anderson George M, Cook Edwin H

机构信息

Yale Child Study Center, Yale University School of Medicine, 230 South Frontage Rd., 06519 New Haven, CT USA ; Department of Laboratory Medicine, Yale University School of Medicine, New Haven, CT USA.

Institute for Juvenile Research, Department of Psychiatry, University of Illinois at Chicago, Chicago, IL USA.

出版信息

Mol Autism. 2016 Mar 29;7:20. doi: 10.1186/s13229-016-0086-8. eCollection 2016.

Abstract

We comment on the recent report entitled "Platelet Studies in Autism Spectrum Disorder Patients and First-Degree Relatives" [Molecular Autism 2015;6:57]. We find it commendable that the authors have investigated platelet factors potentially involved in the well-replicated observation of platelet hyperserotonemia in autism. However, we believe the results need a fuller discussion in the context of prior studies, think that certain aspects of the interpretation need to be reassessed, and attempt to provide a framework for further research in this area.

摘要

我们对最近发表的题为《自闭症谱系障碍患者及其一级亲属的血小板研究》[《分子自闭症》2015年;6:57]的报告发表评论。我们认为作者对可能与自闭症中血小板5-羟色胺水平升高这一反复得到证实的观察结果相关的血小板因子进行了研究,这值得称赞。然而,我们认为这些结果需要结合先前的研究进行更全面的讨论,认为解释的某些方面需要重新评估,并试图为该领域的进一步研究提供一个框架。

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本文引用的文献

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Platelet studies in autism spectrum disorder patients and first-degree relatives.
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Blood serotonin levels in autism spectrum disorder: a systematic review and meta-analysis.
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