Kyaw Aung Ko Ko, Jamalullah Feroz, Vaithieswari Loga, Tan Mein Jin, Zhang Lian, Zhang Jie
Institute of Materials Research and Engineering, Agency for Science, Technology and Research (A*STAR) , 2 Fusionopolis Way, Singapore 138634, Republic of Singapore.
ACS Appl Mater Interfaces. 2016 Apr 20;8(15):9533-9. doi: 10.1021/acsami.6b00108. Epub 2016 Apr 5.
We realize a thermally stable polymer thin film transistor (TFT) that is able to endure the standard autoclave sterilization for reusable medical devices. A thermally stable semiconducting polymer poly[4-(4,4-dihexadecyl-4Hcyclopenta[1,2-b:5,4-b]dithiophen-2-yl)-alt[1,2,5]thiadiazolo [3,4c] pyridine], which is stable up to 350 °C in N2 and 200 °C in air, is used as channel layer, whereas the biocompatible SU-8 polymer is used as a flexible dielectric layer, in addition to conventional SiO2 dielectric layer. Encapsulating with in-house designed composite film laminates as moisture barrier, both TFTs using either SiO2 or SU-8 dielectric layer exhibit good stability in sterilized conditions without significant change in mobility and threshold voltage. After sterilization for 30 min in autoclave, the mobility drops only 15%; from as-fabricated mobility of 1.4 and 1.3 cm(2) V(-1) s(-1) to 1.2 and 1.1 cm(2) V(-1) s(-1) for TFTs with SiO2 and SU-8 dielectric layer, respectively. Our TFT design along with experimental results reveal the opportunity on organic/polymer flexible TFTs in sterilizable/reusable medical device application.
我们实现了一种热稳定的聚合物薄膜晶体管(TFT),它能够承受用于可重复使用医疗设备的标准高压灭菌。一种热稳定的半导体聚合物聚[4-(4,4-二己基-4H-环戊并[1,2-b:5,4-b]二噻吩-2-基)-alt-[1,2,5]噻二唑并[3,4-c]吡啶],在氮气中高达350°C稳定,在空气中200°C稳定,用作沟道层,而生物相容性SU-8聚合物除了传统的SiO2介电层外,还用作柔性介电层。用自行设计的复合薄膜层压板作为防潮层进行封装,使用SiO2或SU-8介电层的两种TFT在灭菌条件下均表现出良好的稳定性,迁移率和阈值电压没有明显变化。在高压灭菌器中灭菌30分钟后,迁移率仅下降15%;对于具有SiO2和SU-8介电层的TFT,分别从制造时的迁移率1.4和1.3 cm² V⁻¹ s⁻¹降至1.2和1.1 cm² V⁻¹ s⁻¹。我们的TFT设计以及实验结果揭示了有机/聚合物柔性TFT在可灭菌/可重复使用医疗设备应用中的机会。