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用于可重复使用医疗设备的热稳定且可消毒的聚合物晶体管。

Thermally Stable and Sterilizable Polymer Transistors for Reusable Medical Devices.

作者信息

Kyaw Aung Ko Ko, Jamalullah Feroz, Vaithieswari Loga, Tan Mein Jin, Zhang Lian, Zhang Jie

机构信息

Institute of Materials Research and Engineering, Agency for Science, Technology and Research (A*STAR) , 2 Fusionopolis Way, Singapore 138634, Republic of Singapore.

出版信息

ACS Appl Mater Interfaces. 2016 Apr 20;8(15):9533-9. doi: 10.1021/acsami.6b00108. Epub 2016 Apr 5.

Abstract

We realize a thermally stable polymer thin film transistor (TFT) that is able to endure the standard autoclave sterilization for reusable medical devices. A thermally stable semiconducting polymer poly[4-(4,4-dihexadecyl-4Hcyclopenta[1,2-b:5,4-b]dithiophen-2-yl)-alt[1,2,5]thiadiazolo [3,4c] pyridine], which is stable up to 350 °C in N2 and 200 °C in air, is used as channel layer, whereas the biocompatible SU-8 polymer is used as a flexible dielectric layer, in addition to conventional SiO2 dielectric layer. Encapsulating with in-house designed composite film laminates as moisture barrier, both TFTs using either SiO2 or SU-8 dielectric layer exhibit good stability in sterilized conditions without significant change in mobility and threshold voltage. After sterilization for 30 min in autoclave, the mobility drops only 15%; from as-fabricated mobility of 1.4 and 1.3 cm(2) V(-1) s(-1) to 1.2 and 1.1 cm(2) V(-1) s(-1) for TFTs with SiO2 and SU-8 dielectric layer, respectively. Our TFT design along with experimental results reveal the opportunity on organic/polymer flexible TFTs in sterilizable/reusable medical device application.

摘要

我们实现了一种热稳定的聚合物薄膜晶体管(TFT),它能够承受用于可重复使用医疗设备的标准高压灭菌。一种热稳定的半导体聚合物聚[4-(4,4-二己基-4H-环戊并[1,2-b:5,4-b]二噻吩-2-基)-alt-[1,2,5]噻二唑并[3,4-c]吡啶],在氮气中高达350°C稳定,在空气中200°C稳定,用作沟道层,而生物相容性SU-8聚合物除了传统的SiO2介电层外,还用作柔性介电层。用自行设计的复合薄膜层压板作为防潮层进行封装,使用SiO2或SU-8介电层的两种TFT在灭菌条件下均表现出良好的稳定性,迁移率和阈值电压没有明显变化。在高压灭菌器中灭菌30分钟后,迁移率仅下降15%;对于具有SiO2和SU-8介电层的TFT,分别从制造时的迁移率1.4和1.3 cm² V⁻¹ s⁻¹降至1.2和1.1 cm² V⁻¹ s⁻¹。我们的TFT设计以及实验结果揭示了有机/聚合物柔性TFT在可灭菌/可重复使用医疗设备应用中的机会。

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