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使用三氧化矿物凝聚体或氢氧化钙进行直接盖髓术的预后因素:2至6年随访

Prognostic factors in direct pulp capping with mineral trioxide aggregate or calcium hydroxide: 2- to 6-year follow-up.

作者信息

Çalışkan Mehmet Kemal, Güneri Pelin

机构信息

Department of Endodontics, School of Dentistry, Ege University, Bornova 35100, İzmir, Turkey.

Department of Oral and Maxillofacial Radiology, School of Dentistry, Ege University, Bornova 35100, İzmir, Turkey.

出版信息

Clin Oral Investig. 2017 Jan;21(1):357-367. doi: 10.1007/s00784-016-1798-z. Epub 2016 Apr 4.

Abstract

OBJECTIVES

The aim of this retrospective study was to evaluate the influence of various predictors on healing outcomes after direct pulp capping (DPC) using either mineral trioxide aggregate (MTA) or calcium hydroxide (CH) as a pulp-dressing agent.

MATERIALS AND METHODS

The present study included 172 mature asymptomatic permanent teeth with carious-exposed pulp. The teeth were treated with DPC, using either MTA or CH, and the treatment outcome was evaluated clinically and radiographically. The effect of potential clinical variables on the treatment outcome of DPC was evaluated clinically and radiographically during a 24-72-month follow-up. In order to assess the cumulative successes of CH and MTA after DPC, Kaplan-Meier survival analysis and log-rank test was used. The subgroups were compared by means of the log-rank test. Also, univariate Cox regression analysis was used to determine hazard ratio of clinical variables.

RESULTS

One hundred and fifty-two teeth of 172 capped teeth were available for follow-up, with an overall recall rate of 87.6 % for MTA vs 89.3 % for CH. The mean period of follow-up was 37.3 (±17.2) months. Overall success rates of 85.9 and 77.6 % in the MTA and CH groups were observed, respectively. The cumulative success rate of both materials was not statistically different when analysed by the Cox proportional hazard regression analysis (P = 0.282). The Kaplan-Meier survival curves revealed that 2-year overall pulp survival was 91.4 %, while the 4- and 6-year survival rates were 84 and 65 %, respectively. None of the clinical variables had a considerable influence on the outcome of DPC (p > 0.05).

CONCLUSIONS

MTA-capped teeth demonstrated a slightly higher success rate than CH, revealing that it can be recommended as a reliable direct pulp-capping material. None of the clinical variables investigated significantly affected posttreatment healing.

CLINICAL RELEVANCE

DPC with MTA is a straightforward procedure with favourable outcome of 24- to 72-month follow-ups in vital mature asymptomatic permanent teeth with cariously exposed pulp, and it may be considered a realistic alternative therapy to RCT.

摘要

目的

本回顾性研究旨在评估使用三氧化矿物凝聚体(MTA)或氢氧化钙(CH)作为牙髓封闭剂进行直接盖髓术(DPC)后,各种预测因素对愈合结果的影响。

材料与方法

本研究纳入172颗龋源性露髓的成熟无症状恒牙。这些牙齿采用MTA或CH进行DPC治疗,并通过临床和影像学评估治疗结果。在24至72个月的随访期间,通过临床和影像学评估潜在临床变量对DPC治疗结果的影响。为了评估DPC后CH和MTA的累积成功率,采用了Kaplan-Meier生存分析和对数秩检验。通过对数秩检验对亚组进行比较。此外,使用单因素Cox回归分析确定临床变量的风险比。

结果

172颗盖髓牙中有152颗可供随访,MTA的总体召回率为87.6%,CH为89.3%。平均随访时间为37.3(±17.2)个月。MTA组和CH组的总体成功率分别为85.9%和77.6%。通过Cox比例风险回归分析,两种材料的累积成功率无统计学差异(P = 0.282)。Kaplan-Meier生存曲线显示,2年总体牙髓生存率为91.4%,而4年和6年生存率分别为84%和65%。没有临床变量对DPC结果有显著影响(p > 0.05)。

结论

MTA盖髓牙的成功率略高于CH,表明它可作为一种可靠的直接盖髓材料推荐。所研究的临床变量均未对治疗后愈合产生显著影响。

临床意义

对于龋源性露髓的活髓成熟无症状恒牙,采用MTA进行DPC是一种简单的操作,在24至72个月的随访中效果良好,可被视为根管治疗的一种现实替代疗法。

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