恩替卡韦治疗乙型肝炎病毒相关性肝硬化患者期间食管静脉曲张的消退情况
Regression of esophageal varices during entecavir treatment in patients with hepatitis-B-virus-related liver cirrhosis.
作者信息
Jwa Hye Young, Cho Yoo-Kyung, Choi Eun Kwang, Kim Heung Up, Song Hyun Joo, Na Soo-Young, Boo Sun-Jin, Jeong Seung Uk, Kim Bong Soo, Lee Byoung-Wook, Song Byung-Cheol
机构信息
Department of Internal Medicine, Jeju National University School of Medicine, Jeju, Korea.
Department of Radiology, Jeju National University School of Medicine, Jeju, Korea.
出版信息
Clin Mol Hepatol. 2016 Mar;22(1):183-7. doi: 10.3350/cmh.2016.22.1.183. Epub 2016 Mar 28.
Recent studies suggest that liver cirrhosis is reversible after administering oral nucleos(t)ide analogue therapy to patients with hepatitis B virus (HBV) infection. However, few studies have addressed whether esophageal varices can regress after such therapy. We report a case of complete regression of esophageal varices during entecavir therapy in patients with HBV-related liver cirrhosis, suggesting that complications of liver cirrhosis such as esophageal varices can regress after the long-term suppression of HBV replication.
近期研究表明，对乙型肝炎病毒（HBV）感染患者给予口服核苷（酸）类似物治疗后，肝硬化是可逆的。然而，很少有研究探讨过接受此类治疗后食管静脉曲张是否会消退。我们报告了1例HBV相关肝硬化患者在恩替卡韦治疗期间食管静脉曲张完全消退的病例，提示肝硬化并发症如食管静脉曲张在长期抑制HBV复制后可以消退。
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