Schlessinger Joel, Saxena Subhash, Mohr Stuart
J Drugs Dermatol. 2016 Apr;15(4):496-503.
There are few creams that have been developed for the purpose of treating the aging hand, yet UV damage and secondary signs of aging on the hands make them one of the most obvious indicators of age outside the face. This study documents results of a 120 day trial using a novel cream preparation containing ingredients including Retinol, Alpha-Arbutin, Kojic Dipalmitate, Azaeleic Acid, Hexylresorcinol, Licorice Root, and other ingredients. Results were tabulated comparing physician and patient assessment scores using a comprehensive scoring assay, which showed significant improvements across eight parameters tested. This was statistically significant for physician ratings of texture, wrinkles and pigment at 120 days versus baseline (P < 0.001). Further research is needed, but the results appear to indicate the benefits of a targeted hand cream in improving the appearance of the aging hand.
专门为治疗手部老化而研发的面霜寥寥无几,然而手部的紫外线损伤和老化的继发性迹象使其成为面部之外最明显的年龄指标之一。本研究记录了一项为期120天的试验结果,该试验使用了一种新型面霜制剂,其成分包括视黄醇、α - 熊果苷、曲酸二棕榈酸酯、壬二酸、己基间苯二酚、甘草根及其他成分。使用综合评分测定法将医生和患者的评估分数制成表格,结果显示在测试的八个参数上有显著改善。在第120天与基线相比,医生对质地、皱纹和色素沉着的评分具有统计学意义(P < 0.001)。虽然还需要进一步研究,但结果似乎表明了一款针对性的护手霜在改善老化手部外观方面的益处。