Motlagh Farid Esmaeili, Ibrahim Fatimah, Rashid Rusdi Abd, Seghatoleslam Tahereh, Habil Hussain
Department of Biomedical Engineering, Faculty of Engineering, University of Malaya, 50603 Kuala Lumpur, Malaysia ; Centre for Innovation in Medical Engineering, Faculty of Engineering, University of Malaya, 50603 Kuala Lumpur, Malaysia ; Centre of Addiction Sciences, University of Malaya, 21st Floor, Wisma Research and Development, Jalan Pantai Baru, 59200 Kuala Lumpur, Malaysia.
Department of Biomedical Engineering, Faculty of Engineering, University of Malaya, 50603 Kuala Lumpur, Malaysia ; Centre for Innovation in Medical Engineering, Faculty of Engineering, University of Malaya, 50603 Kuala Lumpur, Malaysia.
Chin Med. 2016 Apr 5;11:16. doi: 10.1186/s13020-016-0088-7. eCollection 2016.
Acupuncture therapy has been used to treat substance abuse. This study aims to review experimental studies examining the effects of acupuncture on addiction. Research and review articles on acupuncture treatment of substance abuse published between January 2000 and September 2014 were searched using the databases ISI Web of Science Core Collection and EBSCO's MEDLINE Complete. Clinical trial studies on the efficacy of acupuncture therapy for substance abuse were classified according to substance (cocaine, opioid, nicotine, and alcohol), and their treatment protocols, assessments, and findings were examined. A total of 119 studies were identified, of which 85 research articles addressed the efficacy of acupuncture for treating addiction. There were substantial variations in study protocols, particularly regarding treatment duration, frequency of electroacupuncture, duration of stimulation, and choice of acupoints. Contradictory results, intergroup differences, variation in sample sizes, and acupuncture placebo effects made it difficult to evaluate acupuncture effectiveness in drug addiction treatment. This review also identified a lack of rigorous study design, such as control of confounding variables by incorporating sham controls, sufficient sample sizes, reliable assessments, and adequately replicated experiments.
针刺疗法已被用于治疗药物滥用。本研究旨在回顾检验针刺对成瘾影响的实验性研究。使用数据库ISI科学网核心合集和EBSCO的MEDLINE Complete检索了2000年1月至2014年9月间发表的关于针刺治疗药物滥用的研究与综述文章。针刺疗法治疗药物滥用疗效的临床试验研究根据药物(可卡因、阿片类、尼古丁和酒精)进行分类,并对其治疗方案、评估和结果进行了审查。共识别出119项研究,其中85篇研究文章探讨了针刺治疗成瘾的疗效。研究方案存在很大差异,特别是在治疗持续时间、电针频率、刺激持续时间和穴位选择方面。相互矛盾的结果、组间差异、样本量的变化以及针刺安慰剂效应使得难以评估针刺在药物成瘾治疗中的有效性。本综述还发现缺乏严谨的研究设计,例如通过纳入假对照来控制混杂变量、足够的样本量、可靠的评估以及充分重复的实验。