通过多糖-量子点缀合物中的配体交换控制 DNA 凝聚和靶向细胞成像。
Controlled DNA condensation and targeted cellular imaging by ligand exchange in a polysaccharide-quantum dot conjugate.
机构信息
Department of Chemistry, State Key Laboratory of Elemento-Organic Chemistry, Nankai University, Tianjin 300071, P. R. China.
出版信息
Chem Commun (Camb). 2016 May 4;52(36):6087-90. doi: 10.1039/c6cc01571a. Epub 2016 Apr 11.
PMID:27064053
Abstract
A multicomponent supramolecular nanoparticle composed of a polysaccharide-quantum dot conjugate was successfully constructed using a ligand-exchange method, which possessed low cellular cytotoxicity and showed controlled DNA condensation and targeted cellular imaging abilities toward cancer cells.
摘要
采用配体交换法成功构建了由多糖-量子点缀合物组成的多组分超分子纳米粒子，该纳米粒子具有低细胞毒性，并表现出对癌细胞的可控 DNA 缩合和靶向细胞成像能力。
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