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憩室内膀胱肿瘤治疗中的憩室切除术:单机构12年经验

Diverticulectomy in the Management of Intradiverticular Bladder Tumors: A Twelve-Year Experience at a Single Institution.

作者信息

Bourgi Ali, Ayoub Elias, Merhej Sleiman

机构信息

Department of Urology, Hotel-Dieu de France University Hospital, Boulevard Alfred Naccache, Achrafieh, P.O. Box 166830, Beirut, Lebanon.

出版信息

Adv Urol. 2016;2016:2345306. doi: 10.1155/2016/2345306. Epub 2016 Mar 15.

Abstract

Purpose. In this retrospective case review we analyze the outcomes of patients treated for intradiverticular bladder tumors (IDT). Materials and Methods. A retrospective case review was done between January 2002 and May 2014 in Hotel-Dieu de France hospital. The series included 17 patients diagnosed with IDT, all males with a mean age of 49.8 years. Results. One patient was treated with tumor resection and adjuvant BCG instillation with no recurrence on follow-up cystoscopies and urine cytologies. 64% of patients were treated by diverticulectomy. Mean follow-up time was 38.7 months. At the end of the follow-up, 81% were disease-free. One patient had a radical cystectomy 6 months after diverticulectomy for recurrent high grade tumor; another one had a nodal metastasis 10 months after diverticulectomy and was managed with chemotherapy. 29% of patients were treated with radical cystectomy. Mean follow-up time was 28.4 months. No recurrence was documented on annual CT scans. Conclusions. Our data support a conservative approach for tumors confined to the bladder diverticulum, even in high grade or in the presence of CIS provided complete removal is feasible and close follow-up is ensured.

摘要

目的。在这项回顾性病例分析中,我们分析了憩室内膀胱肿瘤(IDT)患者的治疗结果。材料与方法。于2002年1月至2014年5月在法国迪厄医院进行了一项回顾性病例分析。该系列包括17例诊断为IDT的患者,均为男性,平均年龄49.8岁。结果。1例患者接受了肿瘤切除术及辅助卡介苗灌注,随访膀胱镜检查和尿液细胞学检查均无复发。64%的患者接受了憩室切除术。平均随访时间为38.7个月。随访结束时,81%的患者无疾病。1例患者在憩室切除术后6个月因复发性高级别肿瘤接受了根治性膀胱切除术;另1例患者在憩室切除术后10个月出现淋巴结转移,接受了化疗。29%的患者接受了根治性膀胱切除术。平均随访时间为28.4个月。年度CT扫描未记录到复发。结论。我们的数据支持对局限于膀胱憩室的肿瘤采取保守治疗方法,即使是高级别肿瘤或存在原位癌,前提是能够完全切除且确保密切随访。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f1a3/4811051/8d4182db78e8/AU2016-2345306.001.jpg

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