Ahmed Osman, Nguyen Geoffrey C
a Mount Sinai Hospital Centre for Inflammatory Bowel Disease , University of Toronto , Toronto , Canada.
Expert Rev Gastroenterol Hepatol. 2016 Sep;10(9):1005-10. doi: 10.1080/17474124.2016.1179579. Epub 2016 Apr 28.
The rapid advancements in the management of inflammatory bowel disease (IBD) have given clinicians many new therapeutic options. The prevalence of IBD in the elderly is increasing, and the role of these therapeutic agents in the elderly population with IBD is still uncertain.
In this review, we will highlight the challenges facing clinicians managing IBD in the elderly, the considerations to take when starting new medications, when to consider for surgical referral, the potential pitfalls to avoid, and the non-pharmacological management measures that clinicians should be aware of. Expert Commentary: The safety of prescribing new IBD medications in elderly patients must be taken into consideration. Managing comorbidities, polypharmacy, functional status and drug interactions can also be challenging and requires an individualized approach.
炎症性肠病(IBD)管理方面的快速进展为临床医生提供了许多新的治疗选择。IBD在老年人中的患病率正在上升,这些治疗药物在老年IBD患者中的作用仍不确定。
在本综述中,我们将重点介绍临床医生在管理老年IBD患者时面临的挑战、开始使用新药物时的注意事项、何时考虑手术转诊、应避免的潜在陷阱以及临床医生应了解的非药物管理措施。专家评论:必须考虑在老年患者中开具新的IBD药物的安全性。管理合并症、多种药物治疗、功能状态和药物相互作用也可能具有挑战性,需要采取个体化方法。