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精神科入院时使用活性物质如何影响自杀风险和住院时间?

How does active substance use at psychiatric admission impact suicide risk and hospital length-of-stay?

作者信息

Miller Keith A, Hitschfeld Mario J, Lineberry Timothy W, Palmer Brian A

机构信息

a Mayo Medical School , Rochester , Minnesota , USA.

b Mayo Clinic Psychiatry and Psychology , Rochester , Minnesota , USA.

出版信息

J Addict Dis. 2016 Oct-Dec;35(4):291-297. doi: 10.1080/10550887.2016.1177808. Epub 2016 Apr 18.

Abstract

Despite their high prevalence, little is known about the effects of substance use disorders and active substance use on the suicide risk or length-of-stay of psychiatric inpatients. This study examines the relationship between active substance use at the time of psychiatric hospitalization and changes in suicide risk measures and length-of-stay. Admission and discharge ratings on the Suicide Status Form-II-R, diagnoses, and toxicology data from 2,333 unique psychiatric inpatients were examined. Data for patients using alcohol, tetrahydrocannabinol, methamphetamines, cocaine, benzodiazepines, opiates, barbiturates, phencyclidine, and multiple substances on admission were compared with data from 1,426 admissions without substance use. Patients with substance use by toxicology on admission had a 0.9 day shorter length-of-stay compared to toxicology-negative patients. During initial nurse evaluation on the inpatient unit, these patients reported lower suicide measures (i.e., suicidal ideation frequency, overall suicide risk, and wish-to-die). No significant between-group differences were seen at discharge. Patients admitted with a substance use disorder diagnosis had a 1.0 day shorter length-of-stay than those without, while those with a substance use disorder diagnosis and positive toxicology reported the lowest measures of suicidality on admission. These results remained independent of psychiatric diagnosis. For acute psychiatric inpatients, suicide risk is higher and length-of-stay is longer in patients with substance use disorders who are NOT acutely intoxicated compared with patients without a substance use disorder. Toxicology-positive patients are less suicidal on admission and improve faster than their toxicology-negative counterparts. This study gives support to the clinical observation that acutely intoxicated patients may stabilize quickly with regard to suicidal urges and need for inpatient care.

摘要

尽管物质使用障碍和当前物质使用的发生率很高,但对于它们对精神科住院患者自杀风险或住院时间的影响却知之甚少。本研究探讨了精神科住院时当前物质使用与自杀风险指标变化及住院时间之间的关系。我们检查了2333名独特精神科住院患者的自杀状态量表-II-R的入院和出院评分、诊断以及毒理学数据。将入院时使用酒精、四氢大麻酚、甲基苯丙胺、可卡因、苯二氮卓类、阿片类、巴比妥类、苯环己哌啶和多种物质的患者的数据与1426例无物质使用的入院患者的数据进行了比较。与毒理学阴性患者相比,入院时毒理学检查显示有物质使用的患者住院时间短0.9天。在住院部最初的护士评估中,这些患者报告的自杀指标较低(即自杀意念频率、总体自杀风险和想死愿望)。出院时两组之间未观察到显著差异。被诊断为物质使用障碍的患者比未被诊断的患者住院时间短1.0天,而那些被诊断为物质使用障碍且毒理学检查呈阳性的患者在入院时报告的自杀性指标最低。这些结果与精神科诊断无关。对于急性精神科住院患者,与无物质使用障碍的患者相比,未急性中毒的物质使用障碍患者自杀风险更高且住院时间更长。毒理学检查呈阳性的患者入院时自杀倾向较低,且比毒理学检查呈阴性的患者康复得更快。本研究支持了临床观察结果,即急性中毒患者在自杀冲动和住院护理需求方面可能会迅速稳定下来。

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