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分析B型主动脉夹层计算机断层扫描成像的标准化方案。

Standardized Protocol to Analyze Computed Tomography Imaging of Type B Aortic Dissections.

作者信息

Kamman Arnoud V, van Herwaarden Joost A, Orrico Matteo, Nauta Foeke J H, Heijmen Robin H, Moll Frans L, Trimarchi Santi

机构信息

Thoracic Aortic Research Center, Policlinico San Donato IRCCS, San Donato Milanese, Italy Department of Vascular Surgery, University Hospital Utrecht, the Netherlands.

Department of Vascular Surgery, University Hospital Utrecht, the Netherlands.

出版信息

J Endovasc Ther. 2016 Jun;23(3):472-82. doi: 10.1177/1526602816642591. Epub 2016 Apr 18.

Abstract

PURPOSE

To propose a standard measuring protocol for type B aortic dissections so as to improve comparability between studies reporting aortic dimensions.

METHODS

Fifteen computed tomography (CT) scans of type B aortic dissections were measured with a standard protocol by 2 independent observers using postprocessing software. The following parameters were assessed: true, false, and total lumen diameter; true and false lumen volume; and entry tear size, location, and number. Diameters were measured in a perpendicular plane at 2, 10, and 20 cm from the left subclavian artery and 5 cm from the most distal renal artery. True lumen volume was assessed from the left subclavian artery to the aortic bifurcation, while the false lumen volume was from the start to end up to the aortic bifurcation. Entry tear location was assessed in relation to the left subclavian artery. Intra- and interobserver repeatability and agreement were evaluated using the Bland-Altman method, an a priori set of acceptable differences, and Lin's concordance correlation coefficient (LCCC).

RESULTS

Intra- and interobserver mean differences for aortic diameter and true and false lumen volumes were generally within the limits of agreement and the a priori differences; the LCCC showed excellent agreement. Entry tear location, size, and number were difficult to measure in a repeatable manner, with inconsistent correlation coefficients, especially between the 2 observers.

CONCLUSION

This protocol showed acceptable repeatability for aortic diameter and aortic volume measurements. Assessment of entry tears proved challenging and associated with less favorable results. Additionally, investigators are urged to be more transparent regarding the measurement methodology used in studies describing aortic dimensions.

摘要

目的

提出一种B型主动脉夹层的标准测量方案,以提高报告主动脉尺寸的研究之间的可比性。

方法

由2名独立观察者使用后处理软件,按照标准方案对15例B型主动脉夹层的计算机断层扫描(CT)进行测量。评估以下参数:真腔、假腔和总腔直径;真腔和假腔容积;以及入口撕裂的大小、位置和数量。在距左锁骨下动脉2 cm、10 cm和20 cm以及距最远端肾动脉5 cm处的垂直平面上测量直径。从左锁骨下动脉至主动脉分叉评估真腔容积,而假腔容积则从起始处至主动脉分叉处全程评估。根据与左锁骨下动脉的关系评估入口撕裂的位置。使用Bland-Altman方法、一组预先设定的可接受差异以及Lin一致性相关系数(LCCC)评估观察者内和观察者间的重复性及一致性。

结果

观察者内和观察者间主动脉直径以及真腔和假腔容积的平均差异一般在一致性界限和预先设定的差异范围内;LCCC显示出极好的一致性。入口撕裂的位置、大小和数量难以以可重复的方式测量,相关系数不一致,尤其是在2名观察者之间。

结论

该方案在主动脉直径和主动脉容积测量方面显示出可接受的重复性。入口撕裂的评估具有挑战性且结果不太理想。此外, 敦促研究人员在描述主动脉尺寸的研究中,对于所使用的测量方法要更加透明。

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