Lee Ji Hyun, Jung Han Mi, Han Kyung Do, Lee Seung-Hwan, Lee Jun Young, Park Yong Gyu, Park Young Min
Department of Dermatology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul 137-040, Korea.
Acta Derm Venereol. 2017 Jan 4;97(1):77-80. doi: 10.2340/00015555-2441.
Whether metabolic syndrome (MetS) and its components are risk factors for atopic dermatitis (AD) remains unclear. This study investigated the association between MetS and AD in Korean adults. Nationally representative data for 5,007 Korean adults, aged 19-40 years, from the cross-sectional Korea National Health and Nutrition Examination Survey 2010-2011 were analysed. AD in female patients was associated with MetS (p = 0.02) and increased triglyceride level (p = 0.05). After adjusting for confounding factors, the odds ratio for female participants with MetS was 2.92; for central obesity (waist circumference ≥ 85 cm), 1.73; and for hypertriglyceridaemia, 2.20. In this large-scale nationwide study in Korean adults, MetS and its components (central obesity and hypertriglyceridaemia) correlated positively with the presence of AD in women.
代谢综合征(MetS)及其组成部分是否为特应性皮炎(AD)的危险因素仍不明确。本研究调查了韩国成年人中MetS与AD之间的关联。分析了来自2010 - 2011年韩国国家健康与营养检查调查的具有全国代表性的5007名19 - 40岁韩国成年人的数据。女性患者的AD与MetS(p = 0.02)及甘油三酯水平升高(p = 0.05)相关。在调整混杂因素后,患有MetS的女性参与者的比值比为2.92;中心性肥胖(腰围≥85 cm)者为1.73;高甘油三酯血症者为2.20。在这项针对韩国成年人的大规模全国性研究中,MetS及其组成部分(中心性肥胖和高甘油三酯血症)与女性AD的存在呈正相关。