作为全身性疾病体征的舌部病变

A Tongue Lesion as a Sign of a Systemic Disease.

作者信息

Liakou Chrysoula I, Koh Joan, Tsimpidakis Antonios, Rios Katrina, Paskalis Charalabos, Pipilis Athanasios, Kantianis Dimitrios, Georgiadis Thomas, Razis Evangelia

机构信息

Third Department of Medical Oncology, Hygeia Hospital, 15123 Athens, Greece.

Johns Hopkins University Internship Program, Baltimore, MD 21218, USA.

出版信息

Case Rep Med. 2016;2016:6723575. doi: 10.1155/2016/6723575. Epub 2016 Mar 22.

DOI:10.1155/2016/6723575

PMID:27092182

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4820584/

Abstract

Amyloidosis is the extracellular fibril deposition of a variety of proteins, many of which circulate as plasma ingredients. It is a disease difficult to identify due to its nonspecific symptoms and manifestations. Amyloidosis of the tongue, either isolated or part of the systemic disease, is rare and its features resemble those of a tumor. We report the case of a patient with amyloidosis who presented with a tongue lesion, weakness, nonspecific arthritis, and dyspnea on exertion that resulted in multiorgan system failure.

摘要

淀粉样变性是多种蛋白质在细胞外的纤维状沉积，其中许多蛋白质作为血浆成分循环。由于其非特异性症状和表现，这是一种难以识别的疾病。舌淀粉样变性，无论是孤立性的还是全身性疾病的一部分，都很罕见，其特征类似于肿瘤。我们报告了一例淀粉样变性患者的病例，该患者出现舌部病变、虚弱、非特异性关节炎以及劳力性呼吸困难，最终导致多器官系统衰竭。