Tuli Sonal, Gray Matthew
Department of Ophthalmology, University of Florida, Gainesville, Florida, USA.
Curr Opin Ophthalmol. 2016 Jul;27(4):340-7. doi: 10.1097/ICU.0000000000000274.
The purpose of this review is to discuss the options for, and recent developments in, the surgical treatment of corneal infections. Although the mainstay of treatment of corneal infections is topical antimicrobial agents, surgical intervention may be necessary in a number of cases. These include advanced disease at presentation, resistant infections, and progressive ulceration despite appropriate treatment. Prompt and appropriate treatment can make the difference between a good outcome and loss of vision or the eye.
There are a number of surgical therapies available for corneal infections. Preferred therapeutic modalities differ based on the size, causation, and location of the infection but consist of either replacement of the infected tissue or structural support of the tissue to allow healing. Although there are no completely novel therapies that have been developed recently, there have been incremental improvements in the existing treatment modalities making them more effective, easier, and safer.
Several options are available for surgically managing corneal infections. Ophthalmologists should select the optimal procedure based on the individual patient's situation.
本综述旨在探讨角膜感染外科治疗的选择及近期进展。尽管角膜感染治疗的主要手段是局部抗菌药物，但在许多情况下可能需要手术干预。这些情况包括就诊时病情严重、耐药感染以及尽管进行了适当治疗仍出现进行性溃疡。及时且适当的治疗能够决定预后良好与视力丧失或眼球摘除之间的差异。
有多种手术疗法可用于治疗角膜感染。首选的治疗方式因感染的大小、病因和位置而异，但包括更换感染组织或对组织进行结构支撑以促进愈合。尽管最近没有开发出全新的疗法，但现有治疗方式已逐步改进，使其更有效、更简便且更安全。
有多种手术方法可用于处理角膜感染。眼科医生应根据个体患者的情况选择最佳手术方式。
