Department of Cardiology and Angiology I, Heart Center Freiburg University, Freiburg, Germany.
EuroIntervention. 2016 Apr 20;11(13):1541-4. doi: 10.4244/EIJV11I13A296.
While severe tricuspid regurgitation contributes significantly to morbidity and a poor prognosis in heart failure patients, isolated surgical repair of the tricuspid valve is associated with a high mortality, especially in patients with prior surgery. Percutaneous tricuspid valve repair could contribute to the solution of this dilemma. A recently published report demonstrated the feasibility of tricuspid edge-to-edge repair with the MitraClip® system (Abbott Vascular, Santa Clara, CA, USA) using a transjugular route. In a highly symptomatic patient with severe functional tricuspid regurgitation unsuitable for surgery, we aimed to reduce tricuspid regurgitation using a modified deployment technique for the MitraClip system using a femoral access.
A 78-year-old male patient with dilated cardiomyopathy was admitted for his fifth episode of acutely decompensated, predominantly right-sided, heart failure in ten months. Echocardiography showed a moderately to severely reduced left ventricular function and severe functional tricuspid regurgitation. Two clips were deployed in the anterior-septal and posterior-septal commissure of the tricuspid valve, resulting in a significant reduction of the effective regurgitant orifice area. The midterm clinical state of the patient improved.
In our patient with severe functional tricuspid regurgitation and suitable anatomy, transfemoral percutaneous tricuspid valve repair was technically feasible and safe by using a modified deployment technique of a widely used repair system developed for the mitral valve. The procedure can be performed without technical modification of the device via a transfemoral route and under echocardiographic guidance. However, particular anatomic and technical aspects can compromise an initial procedural success and demand specific considerations in the future.
尽管严重的三尖瓣反流会显著增加心力衰竭患者的发病率和预后不良风险,但孤立的三尖瓣手术修复与高死亡率相关,尤其是在既往接受过手术的患者中。经皮三尖瓣修复术可能有助于解决这一困境。最近发表的一份报告表明,使用经颖静脉入路的 MitraClip®系统(美国雅培血管公司,圣克拉拉)进行三尖瓣瓣缘对缘修复是可行的。在一位有严重功能性三尖瓣反流且不适合手术的高度症状性患者中,我们旨在使用改良的经股动脉入路 MitraClip 系统部署技术来降低三尖瓣反流。
一位 78 岁男性患者患有扩张型心肌病,因十个月内第五次急性失代偿性、主要为右侧心力衰竭而入院。超声心动图显示左心室功能中度至重度降低,且存在严重的功能性三尖瓣反流。两个夹子在前隔和后隔三尖瓣连合处展开,有效反流口面积显著减小。患者的中期临床状况改善。
在我们这位有严重功能性三尖瓣反流且适合手术的患者中,通过使用改良的二尖瓣广泛应用修复系统的部署技术,经股动脉入路行经皮三尖瓣修复术在技术上是可行且安全的。该程序可以通过经股动脉入路在超声心动图引导下进行,而无需对器械进行技术修改。然而,特定的解剖和技术方面可能会影响初始程序的成功,并在未来需要具体考虑。