Meldrum J A, Prinsley P R
Department of Otolaryngology,Ipswich Hospital NHS Trust,UK.
Department of Otolaryngology,James Paget University Hospital,Great Yarmouth,UK.
J Laryngol Otol. 2016 Jun;130(6):526-31. doi: 10.1017/S002221511600030X. Epub 2016 Apr 26.
This study aimed to assess the experiences and outcomes of patients who underwent surgical repair of a perilymph fistula in Norfolk, UK.
The study involved a retrospective questionnaire-based patient survey and case note review of patients who had undergone tympanotomy and perilymph fistula repair between 1998 and 2012 in two district general hospitals.
Fourteen patients underwent 20 procedures, of whom 7 completed the pre- and post-operative Vertigo Symptom Scale. In five patients, there was no obvious precipitating cause. Perilymph fistula was precipitated by noise in one patient, by a pressure-increasing event in six patients and by trauma in two patients. The Vertigo Symptom Scale scores showed a statistically significant improvement following surgical repair, from a median of 67 (out of 175) pre-operatively to 19 post-operatively.
In selected patients with vertigo, perilymph fistula should be considered; surgical repair can significantly improve symptoms.
本研究旨在评估在英国诺福克郡接受外淋巴瘘手术修复的患者的经历和治疗结果。
该研究包括一项基于问卷调查的回顾性患者调查，以及对1998年至2012年间在两家地区综合医院接受鼓室切开术和外淋巴瘘修复术的患者病历进行回顾。
14例患者接受了20次手术，其中7例完成了术前和术后眩晕症状量表评估。5例患者无明显诱发原因。1例患者外淋巴瘘由噪声诱发，6例由压力增加事件诱发，2例由外伤诱发。眩晕症状量表评分显示，手术修复后有统计学显著改善，术前中位数为67分（满分175分），术后为19分。
对于选定的眩晕患者，应考虑外淋巴瘘；手术修复可显著改善症状。
