Rodriguez Maria, Ruel Marc
University of Ottawa Heart Institute, Ontario, Canada.
Methodist Debakey Cardiovasc J. 2016 Jan-Mar;12(1):14-9. doi: 10.14797/mdcj-12-1-14.
Coronary artery bypass grafting (CABG) is the gold standard in managing severe coronary artery disease. However, it is associated with prolonged recovery and potential complications, in part due to the invasiveness of the procedure. Less invasive CABG techniques attempt to improve the quality and quantity of life in the same way as surgical revascularization but with fewer complications. Minimally invasive coronary surgery (MICS) through a small thoracotomy allows for complete revascularization with good results in graft patency. Perioperative mortality is low, and there is decreased need for blood transfusion, lower surgical site infection rates, and an earlier return to full physical function. Hybrid coronary revascularization (HCR) attempts to combine the advantages of coronary artery bypass grafting with those of percutaneous coronary intervention. Several studies have shown that HCR provides better short-term outcomes with regard to decreased ventilation and ICU time, reduced need for blood transfusion, and shortened hospital stay. However, the rates for major adverse cardiovascular events and mortality are comparable to conventional CABG, except for patients with a high SYNTAX score who displayed increased mortality rates. There is also strong evidence of a higher need for repeat revascularization with HCR compared to CABG. Overall, MICS and HCR appear to be viable alternatives to conventional CABG, offering a less invasive approach to coronary revascularization, which may be especially beneficial to high-risk patients. This article discusses approaches that deliver the advantages of minimally invasive surgical revascularization that can be adapted by surgeons with minimal investment with regards to training and infrastructure.
冠状动脉旁路移植术(CABG)是治疗严重冠状动脉疾病的金标准。然而,它与恢复时间延长和潜在并发症相关,部分原因是该手术具有侵入性。侵入性较小的CABG技术试图以与手术血运重建相同的方式提高生活质量和数量,但并发症较少。通过小切口开胸进行的微创冠状动脉手术(MICS)可实现完全血运重建,移植血管通畅效果良好。围手术期死亡率低,输血需求减少,手术部位感染率降低,身体功能恢复正常的时间更早。杂交冠状动脉血运重建术(HCR)试图将冠状动脉旁路移植术的优势与经皮冠状动脉介入治疗的优势结合起来。多项研究表明,HCR在减少通气时间和重症监护病房(ICU)停留时间、降低输血需求以及缩短住院时间方面提供了更好的短期结果。然而,除了SYNTAX评分高的患者死亡率增加外,主要不良心血管事件和死亡率与传统CABG相当。也有强有力的证据表明,与CABG相比,HCR需要再次血运重建的比例更高。总体而言,MICS和HCR似乎是传统CABG的可行替代方案,提供了一种侵入性较小的冠状动脉血运重建方法,这可能对高危患者特别有益。本文讨论了能够实现微创外科血运重建优势的方法,外科医生在培训和基础设施方面只需投入最少就能采用这些方法。