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生活在欧洲的第一代中国移民中的心房颤动:一项概念验证研究。

Atrial fibrillation in first generation Chinese migrants living in Europe: A proof of concept study.

作者信息

Modesti Pietro A, Colella Andrea, Zhao Dong

机构信息

Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.

Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.

出版信息

Int J Cardiol. 2016 Jul 15;215:269-72. doi: 10.1016/j.ijcard.2016.04.106. Epub 2016 Apr 16.

Abstract

BACKGROUND

Despite the public health burden of atrial fibrillation (AF) and its complications in China, there is no literature on AF among Chinese living in Europe. The present study was performed to investigate the prevalence of and risk factors for AF in Chinese first generation migrants settled in Europe.

METHODS

A cross-sectional survey was performed in 2014 on Chinese first generation migrants aged 16 to 59years settled in Prato (Italy) adopting principles of community based participatory research. All participants underwent recording of 30s of a single-channel ECG and associations of AF with socio-demographic, anthropometric, clinical factors, and sleep history were examined using logistic regression.

RESULTS

Of the 1608 participants, 12 had AF (0.75%; 95% CI 0.33 to 1.17) - four men and eight women. All subjects with AF had a CHA2DS2VASc index≥1. Although no participant with AF had contraindications to oral anticoagulation, none was treated with oral anticoagulants. At multivariable adjusted logistic regression AF was associated with hypertension with an OR of 4.40 (95% CI 1.09-17.81; p=0.038).

CONCLUSIONS

Chinese are one of the fastest growing migrant populations in Europe and their health has become a key issue to host nations. The issue of AF is to be considered in future prevention programs for elusive ethnic minorities and adequately powered trials specifically designed to investigate AF prevalence and to test prevention approaches are now needed.

摘要

背景

尽管房颤(AF)及其并发症在中国造成了公共卫生负担,但尚无关于居住在欧洲的中国人房颤情况的文献。本研究旨在调查定居在欧洲的第一代中国移民中房颤的患病率及其危险因素。

方法

2014年,采用基于社区参与性研究的原则,对定居在普拉托(意大利)的16至59岁第一代中国移民进行了横断面调查。所有参与者均记录了单通道心电图30秒,并使用逻辑回归分析了房颤与社会人口统计学、人体测量学、临床因素及睡眠史之间的关联。

结果

1608名参与者中,12人患有房颤(0.75%;95%可信区间0.33至1.17),其中4名男性,8名女性。所有房颤患者的CHA2DS2VASc指数均≥1。尽管没有房颤患者存在口服抗凝剂的禁忌证,但无人接受口服抗凝剂治疗。在多变量调整逻辑回归分析中,房颤与高血压相关,比值比为4.40(95%可信区间1.09 - 17.81;p = 0.038)。

结论

中国人是欧洲增长最快的移民群体之一,他们的健康已成为东道国的一个关键问题。在未来针对难以捉摸的少数民族的预防项目中应考虑房颤问题,现在需要开展有足够样本量的专门试验来调查房颤患病率并测试预防方法。

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